Irf9 (Mus musculus)
IRF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00605 (IRF) IPR001346 ENSMUSG00000002325 T244216_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in immune system process and regulation of transcription by RNA polymerase II. Predicted to be located in cytosol. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gland; and sensory organ. Human ortholog(s) of this gene implicated in immunodeficiency 65. Orthologous to human IRF9 (interferon regulatory factor 9). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Irf9
M00173_2.00		 Mus musculus
NNNRAAANN
NNTTTYNNN		 PBM
Badis et al.(2009)
Isgf3g_2853		 (Direct) (Direct)
Irf9
M09240_2.00		 Mus musculus
GAAABHGAAAYT
ARTTTCDVTTTC		 Misc
Kulakovskiy et al.(2013)
IRF9_MOUSE.H11MO.0.C		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
IRF9
M02257_2.00 		Ochotona princeps
DNYRAAAVND
HNBTTTYRNH		 PBM
Weirauch et al.(2014)
pTH9337 		0.837 0.837
IRF9
M02258_2.00 		Sus scrofa
WNYGAAASY
RSTTTCRNW		 PBM
Weirauch et al.(2014)
pTH9287 		0.817 0.817
For this family, TFs with SR scores > 0.700 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00173_2.00 IRF 10 114

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000119477 IRF 29 133
ENSMUSP00000120359 IRF 11 115
ENSMUSP00000120525 IRF 77 181

Links

Other IRF family TFs
Other Mus musculus TFs

46 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
Irf9 Rattus norvegicus ENSRNOG00000019478 I 0.971
ENSDORG00000009268 Dipodomys ordii ENSDORG00000009268 I 0.922
ENSPPYG00000005686 Pongo abelii ENSPPYG00000005686 I 0.875
IRF9 Callithrix jacchus ENSCJAG00000007065 I 0.875
IRF9 Oryctolagus cuniculus ENSOCUG00000028186 I 0.875
IRF9 Gorilla gorilla ENSGGOG00000016046 I 0.865
ENSSTOG00000023450 Ictidomys tridecemlineatus ENSSTOG00000023450 I 0.865
IRF9 Homo sapiens ENSG00000213928 D 0.865
ENSCSAG00000016071 Chlorocebus sabaeus ENSCSAG00000016071 I 0.865
IRF9 Pan troglodytes ENSPTRG00000034494 I 0.865
ENSNLEG00000015294 Nomascus leucogenys ENSNLEG00000015294 I 0.865
ENSMMUG00000012474 Macaca mulatta ENSMMUG00000012474 I 0.865
ENSTSYG00000007445 Tarsius syrichta ENSTSYG00000007445 I 0.856
ENSP00000380073 Macaca fascicularis ENSP00000380073 I 0.856
IRF9 Otolemur garnettii ENSOGAG00000026670 I 0.846
IRF9 Cavia porcellus ENSCPOG00000026474 I 0.846
IRF9 Loxodonta africana ENSLAFG00000026182 I 0.837
IRF9 Ochotona princeps ENSOPRG00000018909 D 0.837
IRF9 Felis catus ENSFCAG00000018849 I 0.827
ENSAMEG00000016347 Ailuropoda melanoleuca ENSAMEG00000016347 I 0.827
IRF9 Canis familiaris ENSCAFG00000012007 I 0.827
IRF9 Equus caballus ENSECAG00000024429 I 0.827
ENSMPUG00000005961 Mustela putorius furo ENSMPUG00000005961 I 0.817
IRF9 Sus scrofa ENSSSCG00000002002 D 0.817
Myotis_brandtii_IRF9_10003711 Myotis brandtii Myotis_brandtii_IRF9_10003711 I 0.808
IRF9 Pteropus vampyrus ENSPVAG00000007716 I 0.808
ENSOARG00000019201 Ovis aries ENSOARG00000019201 I 0.808
IRF9 Myotis lucifugus ENSMLUG00000025255 I 0.808
IRF9 Tursiops truncatus ENSTTRG00000008624 I 0.804
IRF9 Bos taurus ENSBTAG00000005816 I 0.788
ENSBTAP00000044267-D1 Bos grunniens ENSBTAP00000044267-D1 I 0.788
ENSMEUG00000010784 Macropus eugenii ENSMEUG00000010784 I 0.788
IRF9 Monodelphis domestica ENSMODG00000003368 I 0.779
ENSSHAG00000001872 Sarcophilus harrisii ENSSHAG00000001872 I 0.779
IRF9 Procavia capensis ENSPCAG00000015500 I 0.779
irf9 Oryzias latipes ENSORLG00000013335 I 0.760
irf9 Takifugu rubripes ENSTRUG00000017722 I 0.740
ENSONIG00000006624 Oreochromis niloticus ENSONIG00000006624 I 0.731
irf9 Tetraodon nigroviridis ENSTNIG00000008698 I 0.731
ENSACAG00000003946 Anolis carolinensis ENSACAG00000003946 I 0.723
ENSPFOG00000021810 Poecilia formosa ENSPFOG00000021810 I 0.712
irf9 Gasterosteus aculeatus ENSGACG00000001697 I 0.712
ENSGMOG00000002167 Gadus morhua ENSGMOG00000002167 I 0.712
Ogr03980 Ophisaurus gracilis Ogr03980 I 0.702
ENSXMAG00000004567 Xiphophorus maculatus ENSXMAG00000004567 I 0.702