fgenesh_masked-par_contig_1075-abinit-gene-0.8 (Pythium arrhenomanes)
Myb/SANT

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00249 (Myb_DNA-binding) IPR014778 fgenesh_masked-par_contig_1075-abinit-gene-0.8 T270860_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. The encoded protein functions as a chloride channel, making it unique among members of this protein family, and controls ion and water secretion and absorption in epithelial tissues. Channel activation is mediated by cycles of regulatory domain phosphorylation, ATP-binding by the nucleotide-binding domains, and ATP hydrolysis. Mutations in this gene cause cystic fibrosis, the most common lethal genetic disorder in populations of Northern European descent. The most frequently occurring mutation in cystic fibrosis, DeltaF508, results in impaired folding and trafficking of the encoded protein. Multiple pseudogenes have been identified in the human genome. [provided by RefSeq, Aug 2017]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
EPrPR00000019747 Myb 25 70

Links

Other Myb/SANT family TFs
Other Pythium arrhenomanes TFs

2 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
maker-par_contig_2545-snap-gene-0.0 Pythium arrhenomanes maker-par_contig_2545-snap-gene-0.0 N 0.852
maker-pag1_scaffold_266-snap-gene-0.11 Pythium aphanidermatum maker-pag1_scaffold_266-snap-gene-0.11 I 0.666