NCBI Gene Info:Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Involved in positive regulation of fatty acid beta-oxidation by octopamine signaling pathway; positive regulation of fatty acid beta-oxidation by serotonin receptor signaling pathway; and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in several structures, including excretory gland cell; intestine; pharynx; seam cell; and vulval muscle. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human PPARD (peroxisome proliferator activated receptor delta). [provided by Alliance of Genome Resources, Apr 2022] |