CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
Home
Tools
View cart
Bulk downloads
Database stats
Contact us
Help
Update Log
FAQ
Links
How to cite
A1O7_03561
(
Cladophialophora yegresii
)
RFX
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF02257 (RFX_DNA_binding)
IPR003150
A1O7_03561
T317991_2.00
Ensembl (2018-Dec-8)
Link out
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
No direct experiments
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
RFX1
M00066_2.00
Saccharomyces cerevisiae
NSGTTGCYAN
NTRGCAACSN
PBM
Badis et al.(2008)
RFX1_4537
0.677
0.468
RFX1
M07494_2.00
Saccharomyces cerevisiae
BGTTRCYA
TRGYAACV
PBM, CSA and or DIP-chip
Mathelier et al.(2014)
MA0365.1
0.677
0.468
RFX1
M08600_2.00
Saccharomyces cerevisiae
CGTYRBYAYRGYWACM
KGTWRCYRTRVYRACG
Misc
DeBoer et al.(2011)
YLR176C_1478
0.677
0.468
RFX1
M08601_2.00
Saccharomyces cerevisiae
BGTTRCYA
TRGYAACV
Misc
DeBoer et al.(2011)
YLR176C_496
0.677
0.468
RFX1
M11251_2.00
Saccharomyces cerevisiae
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
F$RFX1_02
0.677
0.468
daf-19
M00709_2.00
Caenorhabditis elegans
SGTTRCTADG
CHTAGYAACS
PBM
Narasimhan et al.(2015)
pTH10021
0.651
0.403
For this family, TFs with SR scores >
0.650
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
EXJ63116
RFX
230
306
QVFAMLWLQESCQRSANSVRRDRVFTRYTERCGNERVPTLNPASFGKLVRIIFPNVQTRRLGVRGESKYHYVDLSLI
Links
Other
RFX
family TFs
Other
Cladophialophora yegresii
TFs
260 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
G647_04815
Cladophialophora carrionii
G647_04815
I
0.775
PV04_03763
Capronia semiimmersa
PV04_03763
I
0.774
Z518_01660
Rhinocladiella mackenziei
Z518_01660
I
0.774
A1O3_08026
Capronia epimyces
A1O3_08026
I
0.773
PV07_06647
Cladophialophora immunda
PV07_06647
I
0.773
A1O1_08600
Capronia coronata
A1O1_08600
I
0.772
A1O5_04383
Cladophialophora psammophila
A1O5_04383
I
0.772
HMPREF1120_04684
Exophiala dermatitidis
HMPREF1120_04684
I
0.772
PV05_05335
Exophiala xenobiotica
PV05_05335
I
0.772
PV06_00023
Exophiala oligosperma
PV06_00023
I
0.772
PV08_04071
Exophiala spinifera
PV08_04071
I
0.772
Z517_10332
Fonsecaea pedrosoi
Z517_10332
I
0.772
PV11_01295
Exophiala sideris
PV11_01295
I
0.771
A1O9_03272
Exophiala aquamarina
A1O9_03272
I
0.769
PV10_05596
Exophiala mesophila
PV10_05596
I
0.769
EPUS_04947
Endocarpon pusillum
EPUS_04947
I
0.767
HMPREF1541_04667
Cyphellophora europaea
HMPREF1541_04667
I
0.757
MCYG_06867
Microsporum canis
MCYG_06867
I
0.748
ARB_07111
Arthroderma benhamiae
ARB_07111
I
0.748
H101_06747
Trichophyton interdigitale
H101_06747
I
0.748
H102_04304
Trichophyton rubrum
H102_04304
I
0.748
H105_04329
Trichophyton soudanense
H105_04329
I
0.748
MCYG_06867
Arthroderma otae
MCYG_06867
I
0.748
MGYG_03742
Microsporum gypseum
MGYG_03742
I
0.748
TEQG_02965
Trichophyton equinum
TEQG_02965
I
0.748
TESG_00180
Trichophyton tonsurans
TESG_00180
I
0.748
TRV_04907
Trichophyton verrucosum
TRV_04907
I
0.748
PABG_06744
Paracoccidioides brasiliensis
PABG_06744
I
0.740
PVAR5_6603
Byssochlamys spectabilis
PVAR5_6603
I
0.740
CIMG_05985
Coccidioides immitis
CIMG_05985
I
0.739
CPC735_025690
Coccidioides posadasii
CPC735_025690
I
0.739
PAAG_00480
Paracoccidioides sp lutzii
PAAG_00480
I
0.739
UREG_04378
Uncinocarpus reesii
UREG_04378
I
0.739
PCH_Pc20g01690
Penicillium rubens
PCH_Pc20g01690
I
0.738
PDE_02161
Penicillium oxalicum
PDE_02161
I
0.738
PDIP_47410
Penicillium digitatum
PDIP_47410
I
0.738
PEX1_087840
Penicillium expansum
PEX1_087840
I
0.738
PITC_028740
Penicillium italicum
PITC_028740
I
0.738
U727_0043066021
Penicillium solitum
U727_0043066021
I
0.738
Pc20g01690
Penicillium chrysogenum
Pc20g01690
I
0.738
BDDG_02784
Blastomyces dermatitidis
BDDG_02784
I
0.737
ACLA_009440
Aspergillus clavatus
CADACLAG00001004
I
0.737
CADAFLAG00010851
Aspergillus flavus
CADAFLAG00010851
I
0.737
AFUA_5G06120
Aspergillus fumigatus
CADAFUAG00006202
I
0.737
CADANGAG00013568
Aspergillus niger
CADANGAG00013568
I
0.737
ANIA_02296
Aspergillus nidulans
CADANIAG00008989
I
0.737
CADAORAG00004061
Aspergillus oryzae
CADAORAG00004061
I
0.737
ATEG_09416
Aspergillus terreus
CADATEAG00008983
I
0.737
NFIA_036980
Neosartorya fischeri
CADNFIAG00003299
I
0.737
EURHEDRAFT_516724
Aspergillus ruber
EURHEDRAFT_516724
I
0.737
HCBG_05483
Histoplasma capsulatum
HCBG_05483
I
0.737
PMAA_084960
Talaromyces marneffei
PMAA_084960
I
0.737
TSTA_119980
Talaromyces stipitatus
TSTA_119980
I
0.737
fgenesh1_pg.00162_#_176
Aspergillus carbonarius
fgenesh1_pg.00162_#_176
I
0.737
PMAA_084960
Penicillium marneffei
PMAA_084960
I
0.737
MPH_13091
Macrophomina phaseolina
MPH_13091
I
0.724
SNOG_15366
Stagonospora nodorum
SNOG_15366
I
0.722
COCC4DRAFT_162970
Bipolaris maydis
COCC4DRAFT_162970
I
0.722
COCCADRAFT_29061
Bipolaris zeicola
COCCADRAFT_29061
I
0.722
COCMIDRAFT_23254
Bipolaris oryzae
COCMIDRAFT_23254
I
0.722
COCSADRAFT_34318
Bipolaris sorokiniana
COCSADRAFT_34318
I
0.722
COCVIDRAFT_40879
Bipolaris victoriae
COCVIDRAFT_40879
I
0.722
LEMA_P019700.1
Leptosphaeria maculans
LEMA_P019700.1
I
0.722
PV09_00065
Verruconis gallopava
PV09_00065
I
0.722
SETTUDRAFT_147537
Setosphaeria turcica
SETTUDRAFT_147537
I
0.722
SNOG_15366
Phaeosphaeria nodorum
SNOG_15366
I
0.722
AB07822.1
Alternaria brassicicola
AB07822.1
I
0.722
AUEXF2481DRAFT_78728
Aureobasidium subglaciale
AUEXF2481DRAFT_78728
I
0.721
M437DRAFT_81253
Aureobasidium melanogenum
M437DRAFT_81253
I
0.721
M438DRAFT_393589
Aureobasidium pullulans
M438DRAFT_393589
I
0.721
HMPREF1624_04412
Sporothrix schenckii
HMPREF1624_04412
I
0.718
SPBR_05608
Sporothrix brasiliensis
SPBR_05608
I
0.718
Mycgr3G110369
Zymoseptoria tritici
Mycgr3G110369
I
0.717
PTRG_01267
Pyrenophora triticirepentis
PTRG_01267
I
0.717
PTT_09109
Pyrenophora teres
PTT_09109
I
0.717
estExt_fgenesh1_pg.C_chr_80140
Mycosphaerella graminicola
estExt_fgenesh1_pg.C_chr_80140
I
0.717
BAUCODRAFT_23427
Baudoinia compniacensis
BAUCODRAFT_23427
I
0.716
MYCFIDRAFT_10959
Pseudocercospora fijiensis
MYCFIDRAFT_10959
I
0.716
SEPMUDRAFT_46603
Sphaerulina musiva
SEPMUDRAFT_46603
I
0.716
W97_05844
Coniosporium apollinis
W97_05844
I
0.716
gw1.15.255.1
Mycosphaerella fijiensis
gw1.15.255.1
I
0.716
DOTSEDRAFT_132769
Dothistroma septosporum
DOTSEDRAFT_132769
I
0.715
MAC_02434
Metarhizium acridum
MAC_02434
I
0.715
MAM_06665
Metarhizium album
MAM_06665
I
0.715
TRIATDRAFT_83492
Trichoderma atroviride
TRIATDRAFT_83492
I
0.715
VHEMI10038
Torrubiella hemipterigena
VHEMI10038
I
0.715
estExt_fgenesh2_pg.C_10713
Neurospora discreta
estExt_fgenesh2_pg.C_10713
I
0.715
fgenesh1_pg.C_scaffold_1001176
Cryphonectria parasitica
fgenesh1_pg.C_scaffold_1001176
I
0.715
CPUR_03868
Claviceps purpurea
CPUR_03868
I
0.714
MAJ_05697
Metarhizium majus
MAJ_05697
I
0.714
MANI_023048
Metarhizium anisopliae
MANI_023048
I
0.714
MGU_07283
Metarhizium guizhouense
MGU_07283
I
0.714
SAPIO_CDS9685
Scedosporium apiospermum
SAPIO_CDS9685
I
0.714
X797_002751
Metarhizium robertsii
X797_002751
I
0.714
VDBG_04171
Verticillium albo atrum
VDBG_04171
I
0.713
ACRE_029400
Acremonium chrysogenum
ACRE_029400
I
0.713
CGGC5_15149
Colletotrichum gloeosporioides
CGGC5_15149
I
0.713
Cob_11986
Colletotrichum orbiculare
Cob_11986
I
0.713
FFUJ_02499
Fusarium fujikuroi
FFUJ_02499
I
0.713
FOXG_01471
Fusarium oxysporum
FOXG_01471
I
0.713
FVEG_07837
Fusarium verticillioides
FVEG_07837
I
0.713
MBR_03889
Metarhizium brunneum
MBR_03889
I
0.713
NechaG49316
Fusarium solani
NechaG49316
I
0.713
VDAG_01397
Verticillium dahliae
VDAG_01397
I
0.713
VDBG_04171
Verticillium alfalfae
VDBG_04171
I
0.713
e_gw1.6.922.1
Nectria haematococca
e_gw1.6.922.1
I
0.713
CMQ_5960
Grosmannia clavigera
CMQ_5960
I
0.712
CSUB01_01029
Colletotrichum sublineola
CSUB01_01029
I
0.712
EV44_g5273
Erysiphe necator
EV44_g5273
I
0.712
F503_07504
Ophiostoma piceae uamh
F503_07504
I
0.712
GLRG_03233
Colletotrichum graminicola
GLRG_03233
I
0.712
GMDG_00789
Pseudogymnoascus destructans
GMDG_00789
I
0.712
MBM_03129
Marssonina brunnea
MBM_03129
I
0.712
TRIREDRAFT_69349
Trichoderma reesei
TRIREDRAFT_69349
I
0.712
TRIVIDRAFT_34449
Trichoderma virens
TRIVIDRAFT_34449
I
0.712
UCRPA7_1505
Togninia minima
UCRPA7_1505
I
0.712
V499_05779
Pseudogymnoascus pannorum
V499_05779
I
0.712
BBA_07182
Beauveria bassiana
BBA_07182
I
0.711
CFIO01_07583
Colletotrichum fioriniae
CFIO01_07583
I
0.711
CH063_09103
Colletotrichum higginsianum
CH063_09103
I
0.711
FGRRES_07420
Fusarium graminearum
FGRRES_07420
I
0.711
GGTG_07952
Gaeumannomyces graminis
GGTG_07952
I
0.711
MAPG_07750
Magnaporthe poae
MAPG_07750
I
0.711
OCS_02678
Ophiocordyceps sinensis
OCS_02678
I
0.711
Bcin03g02360
Botrytis cinerea
Bcin03g02360
I
0.710
CCM_03895
Cordyceps militaris
CCM_03895
I
0.710
NEUTE1DRAFT_119738
Neurospora tetrasperma
NEUTE1DRAFT_119738
I
0.710
NCU06701
Neurospora crassa
NCU06701
I
0.710
AOL_s00215g602
Arthrobotrys oligospora
AOL_s00215g602
I
0.709
DRE_06212
Drechslerella stenobrocha
DRE_06212
I
0.709
H072_327
Dactylellina haptotyla
H072_327
I
0.709
MGG_04000
Magnaporthe oryzae
MGG_04000
I
0.708
SBOR_6602
Sclerotinia borealis
SBOR_6602
I
0.708
SS1G_00575
Sclerotinia sclerotiorum
SS1G_00575
I
0.708
THITE_2107553
Thielavia terrestris
THITE_2107553
I
0.708
CTHT_0028340
Chaetomium thermophilum
CTHT_0028340
I
0.707
PFICI_07890
Pestalotiopsis fici
PFICI_07890
I
0.707
MYCTH_2301302
Myceliophthora thermophila
MYCTH_2301302
I
0.704
DEHA2G10868g
Debaryomyces hansenii
DEHA2G10868g
I
0.701
Z519_02210
Cladophialophora bantiana
Z519_02210
N
0.699
S40285_05794
Stachybotrys chlorohalonata
S40285_05794
I
0.698
S40288_01173
Stachybotrys chartarum
S40288_01173
I
0.698
GNLVRS01_PISO0E08012g
Millerozyma farinosa
GNLVRS01_PISO0E08012g
I
0.697
GNLVRS01_PISO0F09355g
Millerozyma farinosa
GNLVRS01_PISO0F09355g
I
0.697
YALI0_E13596g
Yarrowia lipolytica
YALI0_E13596g
I
0.696
FPSE_09383
Fusarium pseudograminearum
FPSE_09383
I
0.695
PAS_chr2-2_0153
Komagataella pastoris
PAS_chr2-2_0153
I
0.695
XP_002492053.1
Pichia pastoris
XP_002492053.1
I
0.695
PICST_78645
Scheffersomyces stipitis
PICST_78645
I
0.694
BGHDH14_bgh05888
Blumeria graminis
BGHDH14_bgh05888
I
0.693
BN7_2967
Wickerhamomyces ciferrii
BN7_2967
I
0.693
SPAPADRAFT_70246
Spathaspora passalidarum
SPAPADRAFT_70246
I
0.693
OIDMADRAFT_184073
Oidiodendron maius
OIDMADRAFT_184073
I
0.692
UV8b_7132
Ustilaginoidea virens
UV8b_7132
I
0.692
PNEG_02893
Pneumocystis murina
PNEG_02893
I
0.691
SMAC_06634
Sordaria macrospora
SMAC_06634
I
0.691
PredSwiss_ASS2010_3110.1
Pneumocystis carinii
PredSwiss_ASS2010_3110.1
I
0.691
PredSwiss_CON653.4
Pneumocystis carinii
PredSwiss_CON653.4
I
0.691
CaO19.11346
Candida albicans
CaO19.11346
I
0.687
CaO19.3865
Candida albicans
CaO19.3865
I
0.687
G210_0560
Candida maltosa
G210_0560
I
0.687
estExt_genewise1_worm.C_chr_6.10133
Pichia stipitis
estExt_genewise1_worm.C_chr_6.10133
I
0.687
CD36_31600
Candida dubliniensis
CD36_31600
I
0.686
NDAI_0G04240
Naumovozyma dairenensis
NDAI_0G04240
I
0.686
sak1
Schizosaccharomyces pombe
SPAC3G9.14
I
0.686
ZYRO0E04642g
Zygosaccharomyces rouxii
ZYRO0E04642g
I
0.686
CPAG_04140
Candida parapsilosis
CPAG_04140
I
0.685
CORT_0D05100
Candida orthopsilosis
CORT_0D05100
I
0.685
CTRG_00624
Candida tropicalis
CTRG_00624
I
0.685
LELG_03203
Lodderomyces elongisporus
LELG_03203
I
0.684
SJAG_04839
Schizosaccharomyces japonicus
SJAG_04839
I
0.684
KNAG_0I01300
Kazachstania naganishii
KNAG_0I01300
I
0.683
KAFR_0I02180
Kazachstania africana
KAFR_0I02180
I
0.682
NCAS_0C04880
Naumovozyma castellii
NCAS_0C04880
I
0.682
Scas_Contig488.2
Saccharomyces castellii
Scas_Contig488.2
I
0.682
CLUG_05348
Candida lusitaniae
CLUG_05348
I
0.681
CLUG_05348
Clavispora lusitaniae
CLUG_05348
I
0.681
LALA0_S03e09428g
Lachancea lanzarotensis
LALA0_S03e09428g
I
0.681
TBLA_0C01490
Tetrapisispora blattae
TBLA_0C01490
I
0.681
GSTUM_00005211001
Tuber melanosporum
GSTUM_00005211001
I
0.679
ZBAI_03427
Zygosaccharomyces bailii
ZBAI_03427
I
0.679
ZBAI_08430
Zygosaccharomyces bailii
ZBAI_08430
I
0.679
CAGL0B04895g
Candida glabrata
CAGL0B04895g
I
0.678
PODANS_2_5740
Podospora anserina
PODANS_2_5740
I
0.678
SOCG_01623
Schizosaccharomyces octosporus
SOCG_01623
I
0.678
SPOG_03909
Schizosaccharomyces cryophilus
SPOG_03909
I
0.678
RFX1
Saccharomyces cerevisiae
YLR176C
D
0.677
14959_Multiple
Saccharomyces mikatae
14959_Multiple
I
0.677
16177_Multiple
Saccharomyces paradoxus
16177_Multiple
I
0.677
KLTH0H12144g
Lachancea thermotolerans
KLTH0H12144g
I
0.676
TDEL_0B05980
Torulaspora delbrueckii
TDEL_0B05980
I
0.676
TPHA_0B03750
Tetrapisispora phaffii
TPHA_0B03750
I
0.676
KLTH0H12144g
Kluyveromyces thermotolerans
KLTH0H12144g
I
0.676
Kwal_214
Kluyveromyces waltii
Kwal_214
I
0.676
AACERI_AaceriAAL010W
Saccharomycetaceae sp ashbya aceri
AACERI_AaceriAAL010W
I
0.675
AGOS_AAL010W
Ashbya gossypii
AGOS_AAL010W
I
0.675
SAKL0D08734g
Lachancea kluyveri
SAKL0D08734g
I
0.675
PGUG_04792
Candida guilliermondii
PGUG_04792
I
0.672
Kpol_457p14
Vanderwaltozyma polyspora
Kpol_457p14
I
0.672
PGUG_04792
Meyerozyma guilliermondii
PGUG_04792
I
0.672
HPODL_00388
Ogataea parapolymorpha
HPODL_00388
I
0.670
KAFR_0H03130
Kazachstania africana
KAFR_0H03130
I
0.668
CAOG_00356
Capsaspora owczarzaki
CAOG_00356
I
0.664
CAGL0H03751g
Candida glabrata
CAGL0H03751g
I
0.664
SPPG_01648
Spizellomyces punctatus
SPPG_01648
I
0.659
ACYPI002124
Acyrthosiphon pisum
ACYPI002124
I
0.659
KUCA_T00003838001
Kuraishia capsulata
KUCA_T00003838001
I
0.658
HelroG82191
Helobdella robusta
HelroG82191
I
0.657
DACRYDRAFT_45233
Dacryopinax sp
DACRYDRAFT_45233
I
0.656
estExt_fgenesh2_pg.C_390014
Monosiga brevicollis
estExt_fgenesh2_pg.C_390014
I
0.656
ENSCING00000022532
Ciona intestinalis
ENSCING00000022532
I
0.655
AMAG_10999
Allomyces macrogynus
AMAG_10999
I
0.654
AMAG_11601
Allomyces macrogynus
AMAG_11601
I
0.654
NEMVEDRAFT_v1g96414
Nematostella vectensis
NEMVEDRAFT_v1g96414
I
0.654
estExt_fgenesh2_pg.C_4710022
Branchiostoma floridae
estExt_fgenesh2_pg.C_4710022
I
0.654
CBG00885
Caenorhabditis briggsae
CBG00885
I
0.653
CJA41991
Caenorhabditis japonica
CJA41991
I
0.653
HelroG70386
Helobdella robusta
HelroG70386
I
0.653
LLOJ001292
Lutzomyia longipalpis
LLOJ001292
I
0.653
PPAI005117
Phlebotomus papatasi
PPAI005117
I
0.653
ADAC010162
Anopheles darlingi
ADAC010162
I
0.652
ENSCSAVG00000006455
Ciona savignyi
ENSCSAVG00000006455
I
0.652
SMU15029830
Schmidtea mediterranea
SMU15029830
I
0.652
AALB009562
Anopheles albimanus
AALB009562
I
0.652
CpipJ_CPIJ004011
Culex pipiens
CpipJ_CPIJ004011
I
0.651
ACYPI000454
Acyrthosiphon pisum
ACYPI000454
I
0.651
CapteG168129
Capitella teleta
CapteG168129
I
0.651
CBN23481
Caenorhabditis brenneri
CBN23481
I
0.651
CBN31487
Caenorhabditis brenneri
CBN31487
I
0.651
CPIJ004011
Culex quinquefasciatus
CPIJ004011
I
0.651
CRE04304
Caenorhabditis remanei
CRE04304
I
0.651
DI09_1p30
Microsporidia sp
DI09_1p30
I
0.651
DI09_91p30
Microsporidia sp
DI09_91p30
I
0.651
rfx1/2/3
Ciona intestinalis
ENSCING00000009186
I
0.651
daf-19
Caenorhabditis elegans
WBGene00000914
D
0.651
AGAP003943
Anopheles gambiae
AGAP003943
I
0.650
M407DRAFT_70388
Tulasnella calospora
M407DRAFT_70388
I
0.650
AARA009842
Anopheles arabiensis
AARA009842
I
0.650
AATE005561
Anopheles atroparvus
AATE005561
I
0.650
ACHR008029
Anopheles christyi
ACHR008029
I
0.650
ACOM024072
Anopheles coluzzii
ACOM024072
I
0.650
ACUA014160
Anopheles culicifacies
ACUA014160
I
0.650
ADIR003347
Anopheles dirus
ADIR003347
I
0.650
AEPI007296
Anopheles epiroticus
AEPI007296
I
0.650
AFUN011233
Anopheles funestus
AFUN011233
I
0.650
AMAM023255
Anopheles maculatus
AMAM023255
I
0.650
AMEC012572
Anopheles melas
AMEC012572
I
0.650
AMEM012406
Anopheles merus
AMEM012406
I
0.650
AMIN000299
Anopheles minimus
AMIN000299
I
0.650
AQUA009139
Anopheles quadriannulatus
AQUA009139
I
0.650
ASTEI00954
Anopheles stephensi
ASTEI00954
I
0.650
csin108803
Clonorchis sinensis
csin108803
I
0.650
ECANG7_04993
Echinococcus canadensis
ECANG7_04993
I
0.650
ECPE_0000690401
Echinostoma caproni
ECPE_0000690401
I
0.650
HmN_000132600
Hymenolepis microstoma
HmN_000132600
I
0.650
HNAJ_0000214001
Hymenolepis nana
HNAJ_0000214001
I
0.650
T265_05437
Opisthorchis viverrini
T265_05437
I
0.650
TASK_0000037701
Taenia asiatica
TASK_0000037701
I
0.650
TsM_000872000
Taenia solium
TsM_000872000
I
0.650
TTAC_0000668301
Hydatigera taeniaeformis
TTAC_0000668301
I
0.650