Sp100 (Mus musculus)
SAND

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF01342 (SAND) IPR000770 ENSMUSG00000026222 T321798_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; chromo shadow domain binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including innate immune response; regulation of signal transduction; and regulation of transcription, DNA-templated. Predicted to be located in cytoplasm and nuclear lumen. Predicted to be part of Mre11 complex. Predicted to be active in nucleus. Is expressed in eye; olfactory placode; and otic pit. Orthologous to human SP100 (SP100 nuclear antigen). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Sp100
M00189_2.00
Mus musculus
NNCGNNNNNN

NNNNNNCGNN
PBM
Badis et al.(2009)
Sp100_2947
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
For this family, TFs with SR scores > 0.843 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00189_2.00 SAND 20 96

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000066399 SAND 382 458
ENSMUSP00000116942 SAND 364 440
ENSMUSP00000118481 SAND 382 458
ENSMUSP00000120267 SAND 15 91
ENSMUSP00000122670 SAND 357 433
ENSMUSP00000122899 SAND 339 415

Links

Other SAND family TFs
Other Mus musculus TFs

1 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action