| NCBI Gene Info:Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within vasculogenesis. Predicted to be located in cytoplasm and nucleus. Is expressed in anterior lateral plate mesoderm and pharyngeal arch. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; autoimmune disease (multiple); dermatomyositis; genital herpes; and systemic scleroderma (multiple). Orthologous to human STAT4 (signal transducer and activator of transcription 4). [provided by Alliance of Genome Resources, Apr 2022] |