CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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osr2
(
Danio rerio
)
C2H2 ZF
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00096 (zf-C2H2)
IPR007087
ENSDARG00000038006
T090899_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within pectoral fin development and pronephros development. Predicted to be active in nucleus. Is expressed in several structures, including gut; intestinal rod; mesoderm; pectoral fin; and pronephros. Orthologous to human OSR2 (odd-skipped related transciption factor 2). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
No direct experiments
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
Osr2
M00132_2.00
Mus musculus
NGCTWCYGNN
NNCRGWAGCN
PBM
Badis et al.(2009)
Osr2_1727
0.824
0.986
Osr1
M00144_2.00
Mus musculus
NVCTHCYNN
NNRGDAGBN
PBM
Badis et al.(2009)
Osr1_3033
0.808
0.971
Osr1
M01174_2.00
Mus musculus
GCTACYGT
ACRGTAGC
PBM
Lambert et al.(2019)
pTH5339
0.808
0.971
OSR1
M04477_2.00
Homo sapiens
NGCTACYGTD
HACRGTAGCN
SELEX
Yin et al.(2017)
OSR1_eDBD_HT-SELEX
0.808
0.971
OSR1
M04478_2.00
Homo sapiens
NGCTACYGTD
HACRGTAGCN
SELEX
Yin et al.(2017)
OSR1_eDBD_Methyl-HT-SELEX
0.808
0.971
odd-2
M00618_2.00
Caenorhabditis elegans
NGCTACYGK
MCRGTAGCN
PBM
Narasimhan et al.(2015)
pTH9150
0.766
0.812
For this family, TFs with SR scores >
0.755
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSDARP00000055394
C2H2 ZF
134
156
FICRFCGRHFTKSYNLLIHERTH
ENSDARP00000055394
C2H2 ZF
162
184
YTCDICHKAFRRQDHLRDHRYIH
ENSDARP00000055394
C2H2 ZF
190
212
FKCQECGKGFCQSRTLAVHKTLH
Links
Other
C2H2 ZF
family TFs
Other
Danio rerio
TFs
134 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy