osr2 (Danio rerio)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSDARG00000038006 T090899_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within pectoral fin development and pronephros development. Predicted to be active in nucleus. Is expressed in several structures, including gut; intestinal rod; mesoderm; pectoral fin; and pronephros. Orthologous to human OSR2 (odd-skipped related transciption factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Osr2
M00132_2.00 		Mus musculus
NGCTWCYGNN
NNCRGWAGCN		 PBM
Badis et al.(2009)
Osr2_1727 		0.824 0.986
Osr1
M00144_2.00 		Mus musculus
NVCTHCYNN
NNRGDAGBN		 PBM
Badis et al.(2009)
Osr1_3033 		0.808 0.971
Osr1
M01174_2.00 		Mus musculus
GCTACYGT
ACRGTAGC		 PBM
Lambert et al.(2019)
pTH5339 		0.808 0.971
OSR1
M04477_2.00 		Homo sapiens
NGCTACYGTD
HACRGTAGCN		 SELEX
Yin et al.(2017)
OSR1_eDBD_HT-SELEX 		0.808 0.971
OSR1
M04478_2.00 		Homo sapiens
NGCTACYGTD
HACRGTAGCN		 SELEX
Yin et al.(2017)
OSR1_eDBD_Methyl-HT-SELEX 		0.808 0.971
odd-2
M00618_2.00 		Caenorhabditis elegans
NGCTACYGK
MCRGTAGCN		 PBM
Narasimhan et al.(2015)
pTH9150 		0.766 0.812
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSDARP00000055394 C2H2 ZF 134 156
ENSDARP00000055394 C2H2 ZF 162 184
ENSDARP00000055394 C2H2 ZF 190 212

Links

Other C2H2 ZF family TFs
Other Danio rerio TFs

134 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
OSR2 Sus scrofa ENSSSCG00000006073 I 0.824
ENSGMOG00000016368 Gadus morhua ENSGMOG00000016368 I 0.824
ENSSHAG00000007793 Sarcophilus harrisii ENSSHAG00000007793 I 0.824
ENSLAFG00000009420 Loxodonta africana ENSLAFG00000009420 I 0.824
osr2 Gasterosteus aculeatus ENSGACG00000003524 I 0.824
OSR2 Homo sapiens ENSG00000164920 D 0.824
osr2 Tetraodon nigroviridis ENSTNIG00000013301 I 0.824
ENSTGUG00000012027 Taeniopygia guttata ENSTGUG00000012027 I 0.824
ENSFCAG00000014220 Felis catus ENSFCAG00000014220 I 0.824
Osr2 Rattus norvegicus ENSRNOG00000011136 I 0.824
ENSLOCG00000009790 Lepisosteus oculatus ENSLOCG00000009790 I 0.824
Osr2 Mus musculus ENSMUSG00000022330 D 0.824
ENSPANG00000012764 Papio anubis ENSPANG00000012764 I 0.824
ENSOCUG00000022383 Oryctolagus cuniculus ENSOCUG00000022383 I 0.824
ENSMPUG00000015246 Mustela putorius furo ENSMPUG00000015246 I 0.824
ENSPFOG00000012273 Poecilia formosa ENSPFOG00000012273 I 0.824
ENSPSIG00000011787 Pelodiscus sinensis ENSPSIG00000011787 I 0.824
ENSMLUG00000013412 Myotis lucifugus ENSMLUG00000013412 I 0.824
Ogr10172 Ophisaurus gracilis Ogr10172 I 0.824
osr2 Takifugu rubripes ENSTRUG00000011070 I 0.824
ENSSTOG00000021263 Ictidomys tridecemlineatus ENSSTOG00000021263 I 0.824
ENSAMXG00000014504 Astyanax mexicanus ENSAMXG00000014504 I 0.824
ENSBTAG00000013213 Bos taurus ENSBTAG00000013213 I 0.824
Gfo_R006005 Geospiza fortis Gfo_R006005 I 0.824
ENSACAG00000016280 Anolis carolinensis ENSACAG00000016280 I 0.824
Alligator_sinensis_CCG020374.1 Alligator sinensis Alligator_sinensis_CCG020374.1 I 0.824
osr2.L Xenopus laevis XB-GENE-864802 I 0.824
osr2.S Xenopus laevis XB-GENE-6254720 I 0.824
ENSXMAG00000002498 Xiphophorus maculatus ENSXMAG00000002498 I 0.824
ENSBTAP00000017584-D1 Bos grunniens ENSBTAP00000017584-D1 I 0.824
ENSCSAG00000012312 Chlorocebus sabaeus ENSCSAG00000012312 I 0.824
ENSCPOG00000020572 Cavia porcellus ENSCPOG00000020572 I 0.824
Afo_R001755 Aptenodytes forsteri Afo_R001755 I 0.808
osr1 Oryzias latipes ENSORLG00000010734 I 0.808
Aan_R015359 Calypte anna Aan_R015359 I 0.808
OSR1 Tursiops truncatus ENSTTRG00000009823 I 0.808
ENSPPYG00000012624 Pongo abelii ENSPPYG00000012624 I 0.808
Brh_R010228 Buceros rhinoceros Brh_R010228 I 0.808
ENSPFOG00000006861 Poecilia formosa ENSPFOG00000006861 I 0.808
osr1 Tetraodon nigroviridis ENSTNIG00000018677 I 0.808
ENSPANG00000025998 Papio anubis ENSPANG00000025998 I 0.808
OSR1 Procavia capensis ENSPCAG00000008261 I 0.808
Ogr01515 Ophisaurus gracilis Ogr01515 I 0.808
Myotis_brandtii_OSR1_10031301 Myotis brandtii Myotis_brandtii_OSR1_10031301 I 0.808
OSR1 Tupaia belangeri ENSTBEG00000004954 I 0.808
ENSSHAG00000010395 Sarcophilus harrisii ENSSHAG00000010395 I 0.808
ENSONIG00000011343 Oreochromis niloticus ENSONIG00000011343 I 0.808
Gfo_R015235 Geospiza fortis Gfo_R015235 I 0.808
ENSSSCG00000027549 Sus scrofa ENSSSCG00000027549 I 0.808
ENSXMAG00000015661 Xiphophorus maculatus ENSXMAG00000015661 I 0.808
ENSP00000272223 Macaca fascicularis ENSP00000272223 I 0.808
osr1 Takifugu rubripes ENSTRUG00000005046 I 0.808
OSR1 Pan troglodytes ENSPTRG00000011683 I 0.808
OSR1 Pteropus vampyrus ENSPVAG00000009615 I 0.808
Osr1 Rattus norvegicus ENSRNOG00000004210 I 0.808
ENSBTAP00000010670-D1 Bos grunniens ENSBTAP00000010670-D1 I 0.808
ENSSTOG00000015454 Ictidomys tridecemlineatus ENSSTOG00000015454 I 0.808
ENSMPUG00000013697 Mustela putorius furo ENSMPUG00000013697 I 0.808
osr1 Danio rerio ENSDARG00000014091 I 0.808
ENSCSAG00000008012 Chlorocebus sabaeus ENSCSAG00000008012 I 0.808
OSR1 Cavia porcellus ENSCPOG00000002025 I 0.808
OSR1 Dasypus novemcinctus ENSDNOG00000001304 I 0.808
Osr1 Dipodomys ordii ENSDORG00000000798 I 0.808
OSR1 Echinops telfairi ENSETEG00000013563 I 0.808
OSR1 Erinaceus europaeus ENSEEUG00000015377 I 0.808
OSR1 Equus caballus ENSECAG00000013593 I 0.808
OSR1 Callithrix jacchus ENSCJAG00000007379 I 0.808
Pvit_07082 Pogona vitticeps Pvit_07082 I 0.808
Tal_R009607 Tyto alba Tal_R009607 I 0.808
CAJ80803 Xenopus laevis CAJ80803 I 0.808
osr1 Xenopus tropicalis XB-GENE-481410 I 0.808
OSR1 Anolis carolinensis ENSACAG00000007059 I 0.808
ENSAMXG00000021239 Astyanax mexicanus ENSAMXG00000021239 I 0.808
OSR1 Canis familiaris ENSCAFG00000003775 I 0.808
OSR1 Bos taurus ENSBTAG00000008113 I 0.808
ENSAPLG00000007971 Anas platyrhynchos ENSAPLG00000007971 I 0.808
ENSFALG00000001785 Ficedula albicollis ENSFALG00000001785 I 0.808
OSR1 Felis catus ENSFCAG00000026754 I 0.808
OSR1 Monodelphis domestica ENSMODG00000010584 I 0.808
OSR1 Myotis lucifugus ENSMLUG00000011374 I 0.808
OSR1 Microcebus murinus ENSMICG00000004493 I 0.808
Cmyd_10011319 Chelonia mydas Cmyd_10011319 I 0.808
Osr1 Mus musculus ENSMUSG00000048387 D 0.808
OSR1 Oryctolagus cuniculus ENSOCUG00000006091 I 0.808
ENSOARG00000016880 Ovis aries ENSOARG00000016880 I 0.808
ENSNLEG00000002004 Nomascus leucogenys ENSNLEG00000002004 I 0.808
OSR1 Meleagris gallopavo ENSMGAG00000014033 I 0.808
ENSMEUG00000016111 Macropus eugenii ENSMEUG00000016111 I 0.808
OSR1 Gallus gallus ENSGALG00000016473 I 0.808
osr1 Gasterosteus aculeatus ENSGACG00000020147 I 0.808
OSR1 Homo sapiens ENSG00000143867 D 0.808
OSR1 Gorilla gorilla ENSGGOG00000016877 I 0.808
ENSLACG00000005856 Latimeria chalumnae ENSLACG00000005856 I 0.808
ENSLOCG00000017186 Lepisosteus oculatus ENSLOCG00000017186 I 0.808
ENSLOCG00000017185 Lepisosteus oculatus ENSLOCG00000017185 I 0.808
OSR1 Loxodonta africana ENSLAFG00000027174 I 0.808
OSR1 Otolemur garnettii ENSOGAG00000003047 I 0.808
ENSPSIG00000011751 Pelodiscus sinensis ENSPSIG00000011751 I 0.801
ENSCING00000006616 Ciona intestinalis ENSCING00000006616 I 0.800
CGI_10012022 Crassostrea gigas CGI_10012022 I 0.797
osr1 Tetraodon nigroviridis ENSTNIG00000018678 I 0.795
ENSPMAG00000001278 Petromyzon marinus ENSPMAG00000001278 I 0.784
LotgiG130661 Lottia gigantea LotgiG130661 I 0.780
LotgiG102775 Lottia gigantea LotgiG102775 I 0.771
nOo.2.0.1.g01159 Onchocerca ochengi nOo.2.0.1.g01159 I 0.768
WBGene00239217 Onchocerca volvulus WBGene00239217 I 0.768
nDi.2.2.2.g05871 Dirofilaria immitis nDi.2.2.2.g05871 I 0.768
nAv.1.0.1.g06169 Acanthocheilonema viteae nAv.1.0.1.g06169 I 0.768
DME_0000745901 Dracunculus medinensis DME_0000745901 I 0.768
EEL_0000443001 Elaeophora elaphi EEL_0000443001 I 0.768
TCNE_0000229401 Toxocara canis TCNE_0000229401 I 0.768
LOAG_00579 Loa loa LOAG_00579 I 0.768
ASU_07002 Ascaris suum ASU_07002 I 0.768
CBG14844 Caenorhabditis briggsae CBG14844 I 0.766
ACOC_0001130401 Angiostrongylus costaricensis ACOC_0001130401 I 0.766
CRE00192 Caenorhabditis remanei CRE00192 I 0.766
odd-2 Caenorhabditis elegans WBGene00003846 D 0.766
CJA04579 Caenorhabditis japonica CJA04579 I 0.766
ACAC_0000529401 Angiostrongylus cantonensis ACAC_0000529401 I 0.766
CBN15373 Caenorhabditis brenneri CBN15373 I 0.766
GPUH_0001513701 Gongylonema pulchrum GPUH_0001513701 I 0.764
NBR_0000990501 Nippostrongylus brasiliensis NBR_0000990501 I 0.764
nLs.2.1.2.g06827 Litomosoides sigmodontis nLs.2.1.2.g06827 I 0.764
BTMF_0000075201 Brugia timori BTMF_0000075201 I 0.764
Bm9236 Brugia malayi Bm9236 I 0.764
ANCCEY_10108 Ancylostoma ceylanicum ANCCEY_10108 I 0.760
DICVIV_08037 Dictyocaulus viviparus DICVIV_08037 I 0.760
ANCDUO_21978 Ancylostoma duodenale ANCDUO_21978 I 0.760
HPLM_0001493201 Haemonchus placei HPLM_0001493201 I 0.760
ANCCAN_29852 Ancylostoma caninum ANCCAN_29852 I 0.760
HCOI00889400 Haemonchus contortus HCOI00889400 I 0.760
SMUV_0000818001 Syphacia muris SMUV_0000818001 I 0.756
NECAME_08408 Necator americanus NECAME_08408 I 0.756
EVEC_0001078501 Enterobius vermicularis EVEC_0001078501 I 0.756