NCBI Gene Info:Enables protein heterodimerization activity and protein homodimerization activity. Acts upstream of or within several processes, including endoderm development; nervous system development; and positive regulation of cyclin-dependent protein serine/threonine kinase activity. Predicted to be active in nucleus. Is expressed in several structures, including EVL; brain; endoderm; neural plate; and presumptive structure. Human ortholog(s) of this gene implicated in spondylocostal dysostosis. Orthologous to human HES7 (hes family bHLH transcription factor 7). [provided by Alliance of Genome Resources, Apr 2022] |