TF Information

her9 *(Danio rerio)* bHLH
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF00010 (HLH)	IPR001092	ENSDARG00000056438	T033706_2.00	Ensembl (2018-Dec-8)	Link out
NCBI Gene Info: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within negative regulation of neurogenesis. Predicted to be active in nucleus. Is expressed in several structures, including axis; central nervous system; neural plate; presumptive hypochord; and pronephros. Orthologous to human HES4 (hes family bHLH transcription factor 4). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
No direct experiments
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
Hes1 M01726_2.00	Mus musculus	NVCACGYKNN	NNMRCGTGBN	PBM Weirauch et al.(2014) pTH5059	0.914	0.982
HES1 M04090_2.00	Homo sapiens	VVCACGYGHM	KDCRCGTGBB	SELEX Yin et al.(2017) HES1_eDBD_HT-SELEX	0.914	0.982
HES1 M09822_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$HES1_Q2	0.914	0.982
HES1 M09823_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$HES1_Q3	0.914	0.982
HES1 M09824_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$HES1_Q4	0.914	0.982
HES1 M09825_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$HES1_Q6	0.914	0.982
HES1 M04091_2.00	Homo sapiens	VNYACNYNHN	NDNRNGTRNB	SELEX Yin et al.(2017) HES1_eDBD_Methyl-HT-SELEX	0.914	0.982
For this family, TFs with SR scores > 0.838* will likely have a similar motif*