NCBI Gene Info:Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within midbrain development; post-embryonic development; and thalamus development. Is expressed in several structures, including central nervous system; future midbrain; and genitourinary system. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia and adult T-cell leukemia. Orthologous to human TAL2 (TAL bHLH transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022] |