Mlxip (Mus musculus)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSMUSG00000038342 T035723_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within nucleocytoplasmic transport. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; craniocervical region bone; rib; testis; and urinary system. Orthologous to human MLXIP (MLX interacting protein). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Mlxip
M01743_2.00		 Mus musculus
HCACGTGV
BCACGTGD		 PBM
Weirauch et al.(2014)
pTH5466		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.838 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M01743_2.00 bHLH 11 61

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000064943 bHLH 718 768
ENSMUSP00000120510 bHLH 164 214

Links

Other bHLH family TFs
Other Mus musculus TFs

38 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
Mlxip Rattus norvegicus ENSRNOG00000001255 I 0.914
ENSMPUG00000002022 Mustela putorius furo ENSMPUG00000002022 I 0.890
MLXIP Myotis lucifugus ENSMLUG00000017230 I 0.890
MLXIP Tursiops truncatus ENSTTRG00000003024 I 0.890
ENSAMEG00000014572 Ailuropoda melanoleuca ENSAMEG00000014572 I 0.890
ENSOARG00000012001 Ovis aries ENSOARG00000012001 I 0.890
ENSSTOG00000001742 Ictidomys tridecemlineatus ENSSTOG00000001742 I 0.890
MLXIP Otolemur garnettii ENSOGAG00000005992 I 0.890
MLXIP Oryctolagus cuniculus ENSOCUG00000011261 I 0.890
MLXIP Sus scrofa ENSSSCG00000009794 I 0.890
ENSP00000312834-D1 Bos grunniens ENSP00000312834-D1 I 0.890
ENSCJAG00000020340 Callithrix jacchus ENSCJAG00000020340 I 0.890
Myotis_brandtii_Mlxip_10021734 Myotis brandtii Myotis_brandtii_Mlxip_10021734 I 0.890
MLXIP Canis familiaris ENSCAFG00000007965 I 0.890
MLXIP Erinaceus europaeus ENSEEUG00000010841 I 0.890
MLXIP Bos taurus ENSBTAG00000004189 I 0.890
MLXIP Felis catus ENSFCAG00000012108 I 0.890
ENSPANG00000019208 Papio anubis ENSPANG00000019208 I 0.887
ENSCSAG00000002159 Chlorocebus sabaeus ENSCSAG00000002159 I 0.887
ENSNLEG00000001393 Nomascus leucogenys ENSNLEG00000001393 I 0.887
ENSP00000312834 Macaca fascicularis ENSP00000312834 I 0.887
MLXIP Homo sapiens ENSG00000175727 I 0.887
ENSPPYG00000005061 Pongo abelii ENSPPYG00000005061 I 0.887
MLXIP Macaca mulatta ENSMMUG00000012652 I 0.887
MLXIP Pan troglodytes ENSPTRG00000005573 I 0.887
MLXIP Gorilla gorilla ENSGGOG00000022345 I 0.887
MLXIP Microcebus murinus ENSMICG00000001163 I 0.877
MLXIP Cavia porcellus ENSCPOG00000003122 I 0.877
MLXIP Equus caballus ENSECAG00000012056 I 0.877
ENSSHAG00000007918 Sarcophilus harrisii ENSSHAG00000007918 I 0.870
MLXIP Monodelphis domestica ENSMODG00000012174 I 0.870
MLXIP Loxodonta africana ENSLAFG00000016436 I 0.870
ENSMEUG00000000276 Macropus eugenii ENSMEUG00000000276 I 0.870
MLXIP Ochotona princeps ENSOPRG00000016617 I 0.864
Mlxip Dipodomys ordii ENSDORG00000005954 I 0.851
MLXIP Procavia capensis ENSPCAG00000007368 I 0.849
MLXIP Dasypus novemcinctus ENSDNOG00000012530 I 0.843