TF Information

Neurog1 *(Rattus norvegicus)* bHLH
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF00010 (HLH)	IPR001092	ENSRNOG00000022405	T037229_2.00	Ensembl (2018-Dec-8)	Link out
NCBI Gene Info: Predicted to enable several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; E-box binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including animal organ morphogenesis; nervous system development; and regulation of transcription, DNA-templated. Predicted to act upstream of or within several processes, including inner ear morphogenesis; positive regulation of exit from mitosis; and regulation of neuron differentiation. Predicted to be located in perikaryon. Predicted to be active in nucleus. Orthologous to human NEUROG1 (neurogenin 1). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
No direct experiments
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
Neurog1 M01748_2.00	Mus musculus	DVMRTATGKB	VMCATAYKBH	PBM Weirauch et al.(2014) pTH5270	0.914	1.000
NEUROG1 M04201_2.00	Homo sapiens	RVCATATGBY	RVCATATGBY	SELEX Yin et al.(2017) NEUROG1_eDBD_HT-SELEX	0.914	1.000
NEUROG1 M04203_2.00	Homo sapiens	RVCATATGBY	RVCATATGBY	SELEX Yin et al.(2017) NEUROG1_FL_HT-SELEX	0.914	1.000
NEUROG1 M04202_2.00	Homo sapiens	RVCATATGBY	RVCATATGBY	SELEX Yin et al.(2017) NEUROG1_eDBD_Methyl-HT-SELEX	0.914	1.000
NEUROG1 M04204_2.00	Homo sapiens	RVCATATGBY	RVCATATGBY	SELEX Yin et al.(2017) NEUROG1_FL_Methyl-HT-SELEX	0.914	1.000
For this family, TFs with SR scores > 0.838* will likely have a similar motif*