CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
Home
Tools
View cart
Bulk downloads
Database stats
Contact us
Help
Update Log
FAQ
Links
How to cite
tai
(
Drosophila melanogaster
)
bHLH
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00010 (HLH)
IPR001092
FBgn0041092
T038450_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Enables nuclear receptor binding activity; nuclear receptor coactivator activity; and transcription coactivator binding activity. Involved in several processes, including border follicle cell migration; germ-line stem-cell niche homeostasis; and positive regulation of border follicle cell migration. Located in nucleus. Is expressed in several structures, including gonad and olfactory receptor neurons. Human ortholog(s) of this gene implicated in acute myeloid leukemia and obesity. Orthologous to human NCOA1 (nuclear receptor coactivator 1); NCOA2 (nuclear receptor coactivator 2); and NCOA3 (nuclear receptor coactivator 3). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
tai
M05997_2.00
Drosophila melanogaster
SACACGTGY
RCACGTGTS
B1H
Zhu et al.(2011)
tai_Clk_SANGER_5_FBgn0041092
(Direct)
(Direct)
tai
M05998_2.00
Drosophila melanogaster
WWMCACGTGDC
GHCACGTGKWW
B1H
Zhu et al.(2011)
tai_SANGER_5_FBgn0041092
(Direct)
(Direct)
tai
M05999_2.00
Drosophila melanogaster
RCACGTGAC
GTCACGTGY
B1H
Zhu et al.(2011)
tgo_tai_SANGER_5_FBgn0041092
(Direct)
(Direct)
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
For this family, TFs with SR scores >
0.838
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
FBpp0292873
bHLH
238
288
INKCNNEKRRREAENGYIEQLSEILTLNKRGDMTSTKPDKAAILNQVVRTY
FBpp0292874
bHLH
238
288
INKCNNEKRRREAENGYIEQLSEILTLNKRGDMTSTKPDKAAILNQVVRTY
FBpp0292875
bHLH
238
288
INKCNNEKRRREAENGYIEQLSEILTLNKRGDMTSTKPDKAAILNQVVRTY
FBpp0292876
bHLH
238
288
INKCNNEKRRREAENGYIEQLSEILTLNKRGDMTSTKPDKAAILNQVVRTY
FBpp0293513
bHLH
238
288
INKCNNEKRRREAENGYIEQLSEILTLNKRGDMTSTKPDKAAILNQVVRTY
FBpp0305597
bHLH
238
288
INKCNNEKRRREAENGYIEQLSEILTLNKRGDMTSTKPDKAAILNQVVRTY
Links
Other
bHLH
family TFs
Other
Drosophila melanogaster
TFs
10 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy