NCBI Gene Info:Enables DNA-binding transcription factor activity; protein heterodimerization activity; and sequence-specific DNA binding activity. Contributes to DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in several processes, including epithelial tube morphogenesis; open tracheal system development; and salivary gland morphogenesis. Located in nucleus. Is expressed in several structures, including embryonic/larval nervous system; embryonic/larval salivary gland; presumptive embryonic/larval system; thoracic segment; and tracheal system. Orthologous to several human genes including NPAS1 (neuronal PAS domain protein 1). [provided by Alliance of Genome Resources, Apr 2022] |