HLH27 (Caenorhabditis elegans)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 HLH27 T040413_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anterior/posterior pattern specification; regulation of neurogenesis; and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including ABpla; ABplp; ABpra; ABprp; and MS. [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
HLH27
M00928_2.00		 Caenorhabditis elegans
CGCRTGKC
GMCAYGCG		 PBM
Grove et al.(2009)
HLH27		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
hlh-25
M00932_2.00 		Caenorhabditis elegans
CGCRTGKB
VMCAYGCG		 PBM
Grove et al.(2009)
HLH25 		0.914 0.990
For this family, TFs with SR scores > 0.838 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00928_2.00 bHLH 73 119
M00928_2.00 bHLH 146 203

DNA Binding Domains

Protein ID Domain From To Sequence
HLH27 bHLH 73 119
HLH27 bHLH 146 203

Links

Other bHLH family TFs
Other Caenorhabditis elegans TFs

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2 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action