nfe2l2b (Danio rerio)
bZIP

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00170 (bZIP_1) IPR011616 ENSDARG00000089697 T059443_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within negative regulation of transcription from RNA polymerase II promoter in response to oxidative stress. Located in cytoplasm and nucleus. Is expressed in several structures, including digestive system; eye; gill; heart; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in Alzheimer's disease; cataract; hepatocellular carcinoma; macular degeneration; and tuberculosis. Orthologous to human NFE2L2 (NFE2 like bZIP transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
NFE2L1
M04008_2.00 		Homo sapiens
RTGACTCAY
RTGAGTCAY		 SELEX
Rodriguez-Martinez et al.(2017)
NFE2L1.1 		0.798 0.562
NFE2L1
M08782_2.00 		Homo sapiens
NATGAYD
HRTCATN		 Misc
Kulakovskiy et al.(2013)
NF2L1_HUMAN.H11MO.0.C 		0.798 0.562
Nfe2l1
M08831_2.00 		Mus musculus
NATGAYD
HRTCATN		 Misc
Kulakovskiy et al.(2013)
NF2L1_MOUSE.H11MO.0.C 		0.798 0.562
NFE2L1
M09925_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFE2L1_Q5 		0.798 0.562
NFE2L1
M09926_2.00 		Homo sapiens
NNNNHWNNATGAC
GTCATNNWDNNNN		 Transfac
Matys et al.(2006)
V$TCF11_01 		0.798 0.562
For this family, TFs with SR scores > 0.782 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSDARP00000106581 bZIP 389 452
ENSDARP00000135355 bZIP 389 452

Links

Other bZIP family TFs
Other Danio rerio TFs

Invalid Input OrderBy

89 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action