JUND (Homo sapiens)
bZIP

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00170 (bZIP_1) IPR011616 ENSG00000130522 T059741_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. This protein has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternative translation initiation site usage results in the production of different isoforms (PMID:12105216). [provided by RefSeq, Nov 2013]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
JUND
M04281_2.00
Homo sapiens
NRTGACGCAYN

NRTGCGTCAYN
SELEX
Yin et al.(2017)
JUND_eDBD_HT-SELEX_1
(Direct) (Direct)
JUND
M04282_2.00
Homo sapiens
BRTKACGTCAYS

SRTGACGTMAYV
SELEX
Yin et al.(2017)
JUND_eDBD_HT-SELEX_2
(Direct) (Direct)
JUND
M04283_2.00
Homo sapiens
BATGASTCATB

VATGASTCATV
SELEX
Yin et al.(2017)
JUND_eDBD_Methyl-HT-SELEX_1
(Direct) (Direct)
JUND
M04284_2.00
Homo sapiens
BRTGACDCATV

BATGHGTCAYV
SELEX
Yin et al.(2017)
JUND_eDBD_Methyl-HT-SELEX_2
(Direct) (Direct)
JUND
M05836_2.00
Homo sapiens
RTGACKCAYH

DRTGMGTCAY
SMiLE-seq
Isakova et al.(2017)
JUND_primary
(Direct) (Direct)
JUND
M05837_2.00
Homo sapiens
NNTKACGTCAB

VTGACGTMANN
SMiLE-seq
Isakova et al.(2017)
JUND_secondary
(Direct) (Direct)
JUND
M07814_2.00
Homo sapiens
NNTGASTCATWHHDRDANH

DNTHYHDDWATGASTCANN
ChIP-seq
Gerstein et al.(2012)
GM12878_JUND_Stanford
(Direct) (Direct)
JUND
M07815_2.00
Homo sapiens
VTGASTCAYCN

NGRTGASTCAB
ChIP-seq
Gerstein et al.(2012)
H1-hESC_JUND_HudsonAlpha
(Direct) (Direct)
JUND
M07816_2.00
Homo sapiens
DGATGASTCAYNBHN

NDVNRTGASTCATCH
ChIP-seq
Gerstein et al.(2012)
HeLa-S3_JUND_Stanford
(Direct) (Direct)
JUND
M07817_2.00
Homo sapiens
VTGASTCAYYHHN

NDDRRTGASTCAB
ChIP-seq
Gerstein et al.(2012)
HepG2_JUND_HudsonAlpha
(Direct) (Direct)
JUND
M07818_2.00
Homo sapiens
BDRTGACKYMWBNNN

NNNVWKRMGTCAYHV
ChIP-seq
Gerstein et al.(2012)
HepG2_JUND_Stanford
(Direct) (Direct)
JUND
M07819_2.00
Homo sapiens
BVTGACGTCAYYNN

NNRRTGACGTCABV
ChIP-seq
Gerstein et al.(2012)
K562_JUND_Stanford
(Direct) (Direct)
JUND
M07820_2.00
Homo sapiens
NGRTGASTCAYNBBB

VVVNRTGASTCAYCN
ChIP-seq
Gerstein et al.(2012)
K562_JUND_UChicago
(Direct) (Direct)
JUND
M08067_2.00
Homo sapiens
DRTGASTCATN

NATGASTCAYH
ChIP-seq
Mathelier et al.(2014)
MA0491.1
(Direct) (Direct)
JUND
M08068_2.00
Homo sapiens
NDNRATGABGTMATN

NATKACVTCATYNHN
ChIP-seq
Mathelier et al.(2014)
MA0492.1
(Direct) (Direct)
JUND
M08797_2.00
Homo sapiens
NRTGACTCABN

NVTGAGTCAYN
Misc
Kulakovskiy et al.(2013)
JUND_HUMAN.H11MO.0.A
(Direct) (Direct)
JUND
M09487_2.00
Homo sapiens
RTGACGTCAYNN

NNRTGACGTCAY
Misc
Heinz et al.(2010)
K562-JunD
(Direct) (Direct)
JUND
M09966_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$JUND_01
(Direct) (Direct)
JUND
M09967_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$JUND_02
(Direct) (Direct)
JUND
M09968_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$JUND_Q6
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Jund
M01001_2.00
Mus musculus
NTGACKYAH

DTRMGTCAN
PBM
Mann et al.(2013)
JUND_UM_HK
0.909 1.000
Jund
M01822_2.00
Mus musculus
RTGACKCAH

DTGMGTCAY
PBM
Weirauch et al.(2014)
pTH5462
0.909 1.000
Jund
M08846_2.00
Mus musculus
RTGACTCABNN

NNVTGAGTCAY
Misc
Kulakovskiy et al.(2013)
JUND_MOUSE.H11MO.0.A
0.909 1.000
Jund
M01000_2.00
Mus musculus
NRTGACTCAN

NTGAGTCAYN
PBM
Mann et al.(2013)
JUND_M_HK
0.909 1.000
jund
M01842_2.00
Xenopus tropicalis
NTGACDCAH

DTGHGTCAN
PBM
Weirauch et al.(2014)
pTH8562
0.908 0.938
Jun
M00995_2.00
Mus musculus
NTGACKYMH

DKRMGTCAN
PBM
Mann et al.(2013)
JUN_UM_HK
0.895 0.891
Jun
M01816_2.00
Mus musculus
NTKACKYAD

HTRMGTMAN
PBM
Weirauch et al.(2014)
pTH4337
0.895 0.891
JUN
M04339_2.00
Homo sapiens
NATGACGTCAYN

NRTGACGTCATN
SELEX
Yin et al.(2017)
JUN_FL_HT-SELEX_1
0.895 0.891
JUN
M04340_2.00
Homo sapiens
NRTGACKCAYN

NRTGMGTCAYN
SELEX
Yin et al.(2017)
JUN_FL_HT-SELEX_2
0.895 0.891
JUN
M05841_2.00
Homo sapiens
NATGACKCATN

NATGMGTCATN
SMiLE-seq
Isakova et al.(2017)
JUN_primary
0.895 0.891
JUN
M05842_2.00
Homo sapiens
NNNDATGACGTMAHNVN

NBNDTKACGTCATHNNN
SMiLE-seq
Isakova et al.(2017)
JUN_secondary
0.895 0.891
JUN
M04037_2.00
Homo sapiens
RTGACKCAY

RTGMGTCAY
SELEX
Rodriguez-Martinez et al.(2017)
JUN.1
0.895 0.891
JUN
M04038_2.00
Homo sapiens
RTGACGTCAT

ATGACGTCAY
SELEX
Rodriguez-Martinez et al.(2017)
JUN.2
0.895 0.891
JUN
M08072_2.00
Homo sapiens
ATKACMTCATHNN

NNDATGAKGTMAT
ChIP-seq
Mathelier et al.(2014)
MA0488.1
0.895 0.891
JUN
M08073_2.00
Homo sapiens
DDDDDRTGASTCAB

VTGASTCAYHHHHH
ChIP-seq
Mathelier et al.(2014)
MA0489.1
0.895 0.891
JUN
M07834_2.00
Homo sapiens
VATDSYHNNNNVVTGASKYM

KRMSTCABBNNNNDRSHATB
ChIP-seq
Gerstein et al.(2012)
H1-hESC_CJUN_Stanford
0.895 0.891
JUN
M07835_2.00
Homo sapiens
DRTGACTCABN

NVTGAGTCAYH
ChIP-seq
Gerstein et al.(2012)
HeLa-S3_CJUN_Stanford
0.895 0.891
JUN
M07836_2.00
Homo sapiens
NRTGACRTCAYYNNN

NNNRRTGAYGTCAYN
ChIP-seq
Gerstein et al.(2012)
HepG2_CJUN_Stanford
0.895 0.891
JUN
M07837_2.00
Homo sapiens
NDRDDRRTGASTCAY

RTGASTCAYYHHYHN
ChIP-seq
Gerstein et al.(2012)
HUVEC_CJUN_Stanford
0.895 0.891
JUN
M07838_2.00
Homo sapiens
NRTGACTCABN

NVTGAGTCAYN
ChIP-seq
Gerstein et al.(2012)
K562_CJUN_Stanford
0.895 0.891
JUN
M08806_2.00
Homo sapiens
DRTGACTCABN

NVTGAGTCAYH
Misc
Kulakovskiy et al.(2013)
JUN_HUMAN.H11MO.0.A
0.895 0.891
Jun
M08837_2.00
Mus musculus
VTGACTCABN

NVTGAGTCAB
Misc
Kulakovskiy et al.(2013)
JUN_MOUSE.H11MO.0.A
0.895 0.891
JUN
M10004_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$CJUN_Q6
0.895 0.891
JUN
M04341_2.00
Homo sapiens
NATGACTCATN

NATGAGTCATN
SELEX
Yin et al.(2017)
JUN_FL_Methyl-HT-SELEX_1
0.895 0.891
JUN
M04342_2.00
Homo sapiens
NATGASTCATN

NATGASTCATN
SELEX
Yin et al.(2017)
JUN_FL_Methyl-HT-SELEX_2
0.895 0.891
JUNB
M04329_2.00
Homo sapiens
BRTGACGTCATN

NATGACGTCAYV
SELEX
Yin et al.(2017)
JUNB_eDBD_HT-SELEX
0.850 0.812
JUNB
M05838_2.00
Homo sapiens
VTGACTCA

TGAGTCAB
SMiLE-seq
Isakova et al.(2017)
JUNB_primary
0.850 0.812
JUNB
M05839_2.00
Homo sapiens
RTKACGTMAY

RTKACGTMAY
SMiLE-seq
Isakova et al.(2017)
JUNB_secondary
0.850 0.812
JUNB
M08070_2.00
Homo sapiens
NRRTGASTCAB

VTGASTCAYYN
ChIP-seq
Mathelier et al.(2014)
MA0490.1
0.850 0.812
JUNB
M07829_2.00
Homo sapiens
NDRTGASTCABNNNB

VNNNVTGASTCAYHN
ChIP-seq
Gerstein et al.(2012)
K562_JUNB_UChicago
0.850 0.812
JUNB
M08803_2.00
Homo sapiens
NVTGACTCABH

DVTGAGTCABN
Misc
Kulakovskiy et al.(2013)
JUNB_HUMAN.H11MO.0.A
0.850 0.812
JUNB
M09992_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$JUNB_Q6
0.850 0.812
JUNB
M04330_2.00
Homo sapiens
BRTGASTCATV

BATGASTCAYV
SELEX
Yin et al.(2017)
JUNB_eDBD_Methyl-HT-SELEX
0.850 0.812
Junb
M00760_2.00
Mus musculus
NNNNNNNN

NNNNNNNN
PBM
Weirauch et al.(2013)
pTH3064
0.850 0.797
Junb
M08838_2.00
Mus musculus
VTGACTCAB

VTGAGTCAB
Misc
Kulakovskiy et al.(2013)
JUNB_MOUSE.H11MO.0.A
0.850 0.797
Jra
M03636_2.00
Drosophila melanogaster
NRTGACGTCAYN

NRTGACGTCAYN
SELEX
Nitta et al.(2015)
Jra_1
0.806 0.672
Jra
M06018_2.00
Drosophila melanogaster
DMTGASTCAYS

SRTGASTCAKH
B1H
Zhu et al.(2011)
kay_Jra_SANGER_5_FBgn0001291
0.806 0.672
For this family, TFs with SR scores > 0.782 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000252818 bZIP 266 329
ENSP00000475153 bZIP 81 144

Links

Other bZIP family TFs
Other Homo sapiens TFs

230 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
mab-23 Caenorhabditis elegans WBGene00003114 D 0.000
WUBG_07178 Wuchereria bancrofti WUBG_07178 I 0.000
L892_g15684 Steinernema scapterisci L892_g15684 I 0.000
L893_g14864 Steinernema glaseri L893_g14864 I 0.000
L898_g15145 Steinernema monticolum L898_g15145 I 0.000
maker-nMf.1.1.scaf01464-snap-gene-0.10 Meloidogyne floridensis maker-nMf.1.1.scaf01464-snap-gene-0.10 I 0.000
nAv.1.0.1.g09488 Acanthocheilonema viteae nAv.1.0.1.g09488 I 0.000
NBR_0001972001 Nippostrongylus brasiliensis NBR_0001972001 I 0.000
NECAME_10548 Necator americanus NECAME_10548 I 0.000
OESDEN_14521 Oesophagostomum dentatum OESDEN_14521 I 0.000
OESDEN_21377 Oesophagostomum dentatum OESDEN_21377 I 0.000
PTRK_0001067200 Parastrongyloides trichosuri PTRK_0001067200 I 0.000
RSKR_0000942000 Rhabditophanes kr3021 RSKR_0000942000 I 0.000
SPAL_0001524600 Strongyloides papillosus SPAL_0001524600 I 0.000
SSTP_0000299900 Strongyloides stercoralis SSTP_0000299900 I 0.000
SVE_0006900 Strongyloides venezuelensis SVE_0006900 I 0.000
L889_g8599 Steinernema feltiae L889_g8599 I 0.000
L596_g22821 Steinernema carpocapsae L596_g22821 I 0.000
HPLM_0002064201 Haemonchus placei HPLM_0002064201 I 0.000
Bm2506 Brugia malayi Bm2506 I 0.000
CBG09659 Caenorhabditis briggsae CBG09659 I 0.000
CBN25704 Caenorhabditis brenneri CBN25704 I 0.000
CRE12856 Caenorhabditis remanei CRE12856 I 0.000
Minc03029 Meloidogyne incognita Minc03029 I 0.000
ACAC_0000050101 Angiostrongylus cantonensis ACAC_0000050101 I 0.000
ACOC_0001070801 Angiostrongylus costaricensis ACOC_0001070801 I 0.000
ALUE_0000029801 Ascaris lumbricoides ALUE_0000029801 I 0.000
ANCCEY_09967 Ancylostoma ceylanicum ANCCEY_09967 I 0.000
ASU_11663 Ascaris suum ASU_11663 I 0.000
BXY_1235100 Bursaphelenchus xylophilus BXY_1235100 I 0.000
DICVIV_00315 Dictyocaulus viviparus DICVIV_00315 I 0.000
GPLIN_000975400 Globodera pallida GPLIN_000975400 I 0.000
HPBE_0000855101 Heligmosomoides bakeri HPBE_0000855101 I 0.000
TCNE_0000373201 Toxocara canis TCNE_0000373201 I 0.000