CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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Atf2
(
Rattus norvegicus
)
bZIP
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00170 (bZIP_1)
IPR011616
ENSRNOG00000001597
T061289_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Enables cAMP response element binding activity. Involved in several processes, including amelogenesis; positive regulation of neuron apoptotic process; and regulation of transcription by RNA polymerase II. Located in nucleus. Used to study hypertension and transient cerebral ischemia. Biomarker of glaucoma and transient cerebral ischemia. Orthologous to human ATF2 (activating transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
No direct experiments
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
Atf2
M01808_2.00
Mus musculus
NRTKAYGYMD
HKRCRTMAYN
PBM
Weirauch et al.(2014)
pTH5083
0.936
1.000
Atf2
M08827_2.00
Mus musculus
VTGACVTCABY
RVTGABGTCAB
Misc
Kulakovskiy et al.(2013)
ATF2_MOUSE.H11MO.0.A
0.936
1.000
Atf2
M09493_2.00
Mus musculus
NNVTGABVTCAB
VTGABVTCABNN
Misc
Heinz et al.(2010)
3T3L1-Atf2_GSE56872
0.936
1.000
Creb5
M02866_2.00
Mus musculus
NATGACGTCAYH
DRTGACGTCATN
SELEX
Jolma et al.(2013)
Creb5_1
0.901
0.812
CREB5
M04299_2.00
Homo sapiens
NVTKACRTMABN
NVTKAYGTMABN
SELEX
Yin et al.(2017)
CREB5_eDBD_HT-SELEX
0.901
0.812
CREB5
M04301_2.00
Homo sapiens
NRTKACGTMAYN
NRTKACGTMAYN
SELEX
Yin et al.(2017)
CREB5_FL_HT-SELEX
0.901
0.812
CREB5
M04300_2.00
Homo sapiens
NRTKACRTCAYN
NRTGAYGTMAYN
SELEX
Yin et al.(2017)
CREB5_eDBD_Methyl-HT-SELEX
0.901
0.812
CREB5
M04302_2.00
Homo sapiens
NATGACRTCAYN
NRTGAYGTCATN
SELEX
Yin et al.(2017)
CREB5_FL_Methyl-HT-SELEX
0.901
0.812
Atf7
M01823_2.00
Mus musculus
HKACGTMAYN
NRTKACGTMD
PBM
Weirauch et al.(2014)
pTH5081
0.886
0.828
asl-1
M01147_2.00
Neurospora crassa
NVTKACGHNN
NNDCGTMABN
PBM
Lambert et al.(2019)
pTH8918
0.787
0.516
For this family, TFs with SR scores >
0.782
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSRNOP00000002174
bZIP
332
395
DPDEKRRKFLERNRAAASRCRQKRKVWVQSLEKKAEDLSSLNGQLQSEVTLLRNEVAQLKQLLL
ENSRNOP00000046001
bZIP
234
297
DPDEKRRKFLERNRAAASRCRQKRKVWVQSLEKKAEDLSSLNGQLQSEVTLLRNEVAQLKQLLL
Links
Other
bZIP
family TFs
Other
Rattus norvegicus
TFs
285 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy