Creb5 (Rattus norvegicus)
bZIP

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00170 (bZIP_1) IPR011616 ENSRNOG00000008622 T061301_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; cAMP response element binding activity; and identical protein binding activity. Predicted to be involved in positive regulation of transcription, DNA-templated; regulation of transcription by RNA polymerase II; and white fat cell differentiation. Predicted to act upstream of or within adipose tissue development; fat cell differentiation; and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human CREB5 (cAMP responsive element binding protein 5). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Creb5
M02866_2.00 		Mus musculus
NATGACGTCAYH
DRTGACGTCATN		 SELEX
Jolma et al.(2013)
Creb5_1 		0.941 1.000
CREB5
M04299_2.00 		Homo sapiens
NVTKACRTMABN
NVTKAYGTMABN		 SELEX
Yin et al.(2017)
CREB5_eDBD_HT-SELEX 		0.941 1.000
CREB5
M04301_2.00 		Homo sapiens
NRTKACGTMAYN
NRTKACGTMAYN		 SELEX
Yin et al.(2017)
CREB5_FL_HT-SELEX 		0.941 1.000
CREB5
M04300_2.00 		Homo sapiens
NRTKACRTCAYN
NRTGAYGTMAYN		 SELEX
Yin et al.(2017)
CREB5_eDBD_Methyl-HT-SELEX 		0.941 1.000
CREB5
M04302_2.00 		Homo sapiens
NATGACRTCAYN
NRTGAYGTCATN		 SELEX
Yin et al.(2017)
CREB5_FL_Methyl-HT-SELEX 		0.941 1.000
Atf7
M01823_2.00 		Mus musculus
HKACGTMAYN
NRTKACGTMD		 PBM
Weirauch et al.(2014)
pTH5081 		0.911 0.812
Atf2
M01808_2.00 		Mus musculus
NRTKAYGYMD
HKRCRTMAYN		 PBM
Weirauch et al.(2014)
pTH5083 		0.901 0.812
Atf2
M08827_2.00 		Mus musculus
VTGACVTCABY
RVTGABGTCAB		 Misc
Kulakovskiy et al.(2013)
ATF2_MOUSE.H11MO.0.A 		0.901 0.812
Atf2
M09493_2.00 		Mus musculus
NNVTGABVTCAB
VTGABVTCABNN		 Misc
Heinz et al.(2010)
3T3L1-Atf2_GSE56872 		0.901 0.812
For this family, TFs with SR scores > 0.782 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSRNOP00000036595 bZIP 426 489
ENSRNOP00000073400 bZIP 234 297

Links

Other bZIP family TFs
Other Rattus norvegicus TFs

Invalid Input OrderBy

233 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action