slbo (Drosophila melanogaster)
bZIP

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00170 (bZIP_1) IPR011616 FBgn0005638 T062073_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in border follicle cell migration; positive regulation of border follicle cell migration; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including embryonic/larval digestive system; embryonic/larval spiracle; nephrocyte; ovary; and presumptive embryonic/larval system. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to several human genes including CEBPA (CCAAT enhancer binding protein alpha); CEBPD (CCAAT enhancer binding protein delta); and CEBPE (CCAAT enhancer binding protein epsilon). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
slbo
M03642_2.00
Drosophila melanogaster
NRTTRCGYAAYN

NRTTRCGYAAYN
SELEX
Nitta et al.(2015)
slbo_1
(Direct) (Direct)
slbo
M03643_2.00
Drosophila melanogaster
NRTTRCGYAAYN

NRTTRCGYAAYN
SELEX
Nitta et al.(2015)
slbo_2
(Direct) (Direct)
slbo
M06021_2.00
Drosophila melanogaster
ATTRCVMA

TKBGYAAT
B1H
Zhu et al.(2011)
slbo_FlyReg_FBgn0005638
(Direct) (Direct)
slbo
M06022_2.00
Drosophila melanogaster
DRTKWCGYAAB

VTTRCGWMAYH
B1H
Zhu et al.(2011)
slbo_SANGER_5_FBgn0005638
(Direct) (Direct)
slbo
M07540_2.00
Drosophila melanogaster
ATTRCVMA

TKBGYAAT
DNaseI footprinting
Mathelier et al.(2014)
MA0244.1
(Direct) (Direct)
slbo
M10035_2.00
Drosophila melanogaster Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
I$CEBP_Q6
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
For this family, TFs with SR scores > 0.782 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
FBpp0072179 bZIP 364 424
FBpp0308452 bZIP 364 424

Links

Other bZIP family TFs
Other Drosophila melanogaster TFs

30 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
GL20490 Drosophila persimilis FBgn0158085 I 0.874
GD24965 Drosophila simulans FBgn0196278 I 0.874
GE11469 Drosophila yakuba FBgn0229274 I 0.874
GG19941 Drosophila erecta FBgn0112141 I 0.874
GM11843 Drosophila sechellia FBgn0166784 I 0.874
GA18129 Drosophila pseudoobscura FBgn0078137 I 0.874
GF13466 Drosophila ananassae FBgn0090495 I 0.871
GI18345 Drosophila mojavensis FBgn0141084 I 0.871
MDOA000553 Musca domestica MDOA000553 I 0.855
AMEC014175 Anopheles melas AMEC014175 I 0.848
AMAM003092 Anopheles maculatus AMAM003092 I 0.848
AFUN001809 Anopheles funestus AFUN001809 I 0.848
AMEM011145 Anopheles merus AMEM011145 I 0.848
ASIS014644 Anopheles sinensis ASIS014644 I 0.848
AEPI002124 Anopheles epiroticus AEPI002124 I 0.848
AQUA005181 Anopheles quadriannulatus AQUA005181 I 0.848
AMIN008497 Anopheles minimus AMIN008497 I 0.848
AARA005525 Anopheles arabiensis AARA005525 I 0.848
AGAP011096 Anopheles gambiae AGAP011096 I 0.848
ACUA022787 Anopheles culicifacies ACUA022787 I 0.848
AATE016567 Anopheles atroparvus AATE016567 I 0.848
AALB010747 Anopheles albimanus AALB010747 I 0.848
ACHR008909 Anopheles christyi ACHR008909 I 0.848
ACOM023078 Anopheles coluzzii ACOM023078 I 0.848
LLOJ006051 Lutzomyia longipalpis LLOJ006051 I 0.842
PPAI007786 Phlebotomus papatasi PPAI007786 I 0.842
BGIBMGA013687 Bombyx mori BGIBMGA013687 I 0.786
HMEL005312 Heliconius melpomene HMEL005312 I 0.786
KGM_12457 Danaus plexippus KGM_12457 I 0.786