atf-6 (Caenorhabditis elegans)
bZIP

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00170 (bZIP_1) IPR011616 WBGene00000222 T069395_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in ATF6-mediated unfolded protein response; positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response; and response to tunicamycin. Predicted to be active in nucleus. Is expressed in several structures, including intestine; muscle cell; pharyngeal gland cell; rectum; and vulva. Human ortholog(s) of this gene implicated in achromatopsia 7. Orthologous to human ATF6 (activating transcription factor 6) and ATF6B (activating transcription factor 6 beta). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
atf-6
M00594_2.00		 Caenorhabditis elegans
NYKACGTDD
HHACGTMRN		 PBM
Narasimhan et al.(2015)
pTH9159		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.782 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00594_2.00 bZIP 52 108

DNA Binding Domains

Protein ID Domain From To Sequence
F45E6.2 bZIP 248 304

Links

Other bZIP family TFs
Other Caenorhabditis elegans TFs

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3 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action