fos-1 (Caenorhabditis elegans)
bZIP

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00170 (bZIP_1) IPR011616 WBGene00001345 T069399_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables several functions, including RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; enzyme binding activity; and identical protein binding activity. Involved in several processes, including basement membrane disassembly; negative regulation of stress response to copper ion; and regulation of transcription by RNA polymerase II. Located in nucleus. Part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including gonad; neurons; uterine pi cell; ventral uterine precursor; and vulval cell. Orthologous to several human genes including FOSL1 (FOS like 1, AP-1 transcription factor subunit); FOSL2 (FOS like 2, AP-1 transcription factor subunit); and FOS (Fos proto-oncogene, AP-1 transcription factor subunit). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
fos-1
M01144_2.00
Caenorhabditis elegans
TGACTCA

TGAGTCA
PBM
Lambert et al.(2019)
pTH10020
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
For this family, TFs with SR scores > 0.782 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M01144_2.00 bZIP 51 114

DNA Binding Domains

Protein ID Domain From To Sequence
F29G9.4a bZIP 25 88
F29G9.4b bZIP 161 224

Links

Other bZIP family TFs
Other Caenorhabditis elegans TFs

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13 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action