zfh2 (Drosophila melanogaster)
C2H2 ZF,Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2)
PF00046 (Homeobox) 		IPR007087
IPR001356 		FBgn0004607 T076056_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in imaginal disc-derived wing morphogenesis and nervous system development. Located in nucleus. Is expressed in several structures, including ectoderm anlage; embryonic/larval nervous system; gastrula embryo; imaginal disc; and presumptive embryonic/larval system. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to several human genes including ZFHX3 (zinc finger homeobox 3) and ZFHX4 (zinc finger homeobox 4). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
FBpp0088139 C2H2 ZF 559 582
FBpp0088139 C2H2 ZF 614 638
FBpp0088139 C2H2 ZF 732 756
FBpp0088139 C2H2 ZF 1210 1233
FBpp0088139 C2H2 ZF 1438 1462
FBpp0088139 C2H2 ZF 1513 1535
FBpp0088139 C2H2 ZF 1541 1564
FBpp0088139 Homeodomain 1798 1854
FBpp0088139 Homeodomain 2155 2211
FBpp0088139 C2H2 ZF 2234 2256
FBpp0088139 C2H2 ZF 2371 2393
FBpp0088139 Homeodomain 2761 2817
FBpp0297996 C2H2 ZF 559 582
FBpp0297996 C2H2 ZF 614 638
FBpp0297996 C2H2 ZF 732 756
FBpp0297996 C2H2 ZF 1210 1233
FBpp0297996 C2H2 ZF 1438 1462
FBpp0297996 C2H2 ZF 1513 1535
FBpp0297996 C2H2 ZF 1541 1564
FBpp0297996 Homeodomain 1796 1852
FBpp0297996 Homeodomain 2153 2209
FBpp0297996 C2H2 ZF 2232 2254
FBpp0297996 C2H2 ZF 2369 2391
FBpp0297996 Homeodomain 2759 2815
FBpp0305133 C2H2 ZF 559 582
FBpp0305133 C2H2 ZF 614 638
FBpp0305133 C2H2 ZF 732 756
FBpp0305133 C2H2 ZF 1210 1233
FBpp0305133 C2H2 ZF 1438 1462
FBpp0305133 C2H2 ZF 1513 1535
FBpp0305133 C2H2 ZF 1541 1564
FBpp0305133 Homeodomain 1798 1854
FBpp0305133 Homeodomain 2155 2211
FBpp0305133 C2H2 ZF 2234 2256
FBpp0305133 C2H2 ZF 2371 2393
FBpp0305133 Homeodomain 2761 2805

Links

Other C2H2 ZF,Homeodomain family TFs
Other Drosophila melanogaster TFs

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11 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action