NCBI Gene Info:Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within positive regulation of type I interferon production and regulation of neurogenesis. Located in nucleus. Is expressed in several structures, including anterior neural keel; anterior neural rod; central nervous system; pleuroperitoneal region; and posterior neural rod. Human ortholog(s) of this gene implicated in acute promyelocytic leukemia. Orthologous to human ZBTB16 (zinc finger and BTB domain containing 16). [provided by Alliance of Genome Resources, Apr 2022] |