| NCBI Gene Info:Enables DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including sensory epithelium regeneration; sensory system development; and spinal cord motor neuron differentiation. Predicted to be part of transcription repressor complex. Predicted to be active in nucleus. Is expressed in several structures, including nervous system; optic cup; pancreas primordium; presumptive telencephalon; and trigeminal placode. Orthologous to human INSM1 (INSM transcriptional repressor 1). [provided by Alliance of Genome Resources, Apr 2022] |