ZNF614 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000142556 T094950_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
ZNF614
M07593_2.00
Homo sapiens
AGMTSARRTCABNMBWCWNRY

RYNWGWVKNVTGAYYTSAKCT
ChIP-seq+ChIP-exo
Barazandeh et al.(2018)
ZNF614.MEME.OriginalMapping
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000270649 C2H2 ZF 287 309
ENSP00000270649 C2H2 ZF 315 337
ENSP00000270649 C2H2 ZF 343 365
ENSP00000270649 C2H2 ZF 371 393
ENSP00000270649 C2H2 ZF 399 421
ENSP00000270649 C2H2 ZF 427 449
ENSP00000270649 C2H2 ZF 455 477
ENSP00000270649 C2H2 ZF 483 505
ENSP00000270649 C2H2 ZF 511 533
ENSP00000270649 C2H2 ZF 539 561

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

9 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ZNF614 Pan troglodytes ENSPTRG00000011403 I 0.823
ZNF614 Gorilla gorilla ENSGGOG00000008538 I 0.821
ENSPANG00000010091 Papio anubis ENSPANG00000010091 I 0.817
ZNF614 Callithrix jacchus ENSCJAG00000036513 I 0.817
ENSCSAG00000001997 Chlorocebus sabaeus ENSCSAG00000001997 I 0.817
ENSPPYG00000010332 Pongo abelii ENSPPYG00000010332 I 0.817
ENSNLEG00000005982 Nomascus leucogenys ENSNLEG00000005982 I 0.816
ZNF614 Tupaia belangeri ENSTBEG00000002386 I 0.809
ENSMICG00000004052 Microcebus murinus ENSMICG00000004052 I 0.800