ZNF597 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000167981 T095067_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene encodes a protein with multiple zinc finger domains. Loss of the related gene in rodents results in defects in neural development and embryonic lethality in mutant homozygotes. This gene is adjacent to a differentially methylated region (DMR) and is imprinted and maternally expressed. [provided by RefSeq, Nov 2015]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
ZNF597
M04531_2.00
Homo sapiens
NKMCGCCATYTTGN

NCAARATGGCGKMN
SELEX
Yin et al.(2017)
ZNF597_FL_HT-SELEX
(Direct) (Direct)
ZNF597
M04532_2.00
Homo sapiens
GGCGGCCATYTTGD

HCAARATGGCCGCC
SELEX
Yin et al.(2017)
ZNF597_FL_Methyl-HT-SELEX
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000301744 C2H2 ZF 156 178
ENSP00000301744 C2H2 ZF 184 206
ENSP00000301744 C2H2 ZF 212 234
ENSP00000301744 C2H2 ZF 240 262
ENSP00000301744 C2H2 ZF 341 363
ENSP00000301744 C2H2 ZF 397 419

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

4 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ENSNLEG00000009655 Nomascus leucogenys ENSNLEG00000009655 I 0.827
ZNF597 Gorilla gorilla ENSGGOG00000007436 I 0.825
ZNF597 Callithrix jacchus ENSCJAG00000019643 I 0.822
ZNF597 Pan troglodytes ENSPTRG00000007699 I 0.821