CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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HINFP
(
Homo sapiens
)
C2H2 ZF
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00096 (zf-C2H2)
IPR007087
ENSG00000172273
T095118_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
This gene encodes a transcription factor that interacts with methyl-CpG-binding protein-2 (MBD2), a component of the MeCP1 histone deacetylase (HDAC) complex, and plays a role in DNA methylation and transcription repression. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Aug 2011]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
HINFP
M02907_2.00
Homo sapiens
BVRCGTCCGCNN
NNGCGGACGYBV
SELEX
Jolma et al.(2013)
HINFP1_1
(Direct)
(Direct)
HINFP
M02908_2.00
Homo sapiens
GCGGACGYTRSRRCGTCCGC
GCGGACGYYSYARCGTCCGC
SELEX
Jolma et al.(2013)
HINFP1_2
(Direct)
(Direct)
HINFP
M02909_2.00
Homo sapiens
GCGGACSBKSVRCGTCCGC
GCGGACGYBSMVSGTCCGC
SELEX
Jolma et al.(2013)
HINFP1_3
(Direct)
(Direct)
HINFP
M08918_2.00
Homo sapiens
BWACGTCCGHBDNSNH
DNSNHVDCGGACGTWV
Misc
Kulakovskiy et al.(2013)
HINFP_HUMAN.H11MO.0.C
(Direct)
(Direct)
HINFP
M10262_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$MIZF_01
(Direct)
(Direct)
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
For this family, TFs with SR scores >
0.755
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSP00000318085
C2H2 ZF
170
193
LCGWKGCTCTFKDRSKLREHLRSH
ENSP00000318085
C2H2 ZF
200
220
ACPTCGGMFANNTKFLDHIRR
ENSP00000318085
C2H2 ZF
229
251
FQCSHCSKRFATERLLRDHMRNH
ENSP00000318085
C2H2 ZF
255
278
YKCPLCDMTCPLPSSLRNHMRFRH
ENSP00000318085
C2H2 ZF
284
306
FKCDCCDYSCKNLIDLQKHLDTH
ENSP00000318085
C2H2 ZF
345
368
YKCHVCDKCFTRGNNLTVHLRKKH
ENSP00000436815
C2H2 ZF
170
193
LCGWKGCTCTFKDRSKLREHLRSH
ENSP00000436815
C2H2 ZF
200
220
ACPTCGGMFANNTKFLDHIRR
ENSP00000436815
C2H2 ZF
229
251
FQCSHCSKRFATERLLRDHMRNH
ENSP00000436815
C2H2 ZF
255
278
YKCPLCDMTCPLPSSLRNHMRFRH
ENSP00000436815
C2H2 ZF
284
306
FKCDCCDYSCKNLIDLQKHLDTH
ENSP00000436815
C2H2 ZF
345
368
YKCHVCDKCFTRGNNLTVHLRKKH
Links
Other
C2H2 ZF
family TFs
Other
Homo sapiens
TFs
30 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy