ZNF335 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000198026 T095367_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
The protein encoded by this gene enhances transcriptional activation by ligand-bound nuclear hormone receptors. However, it does this not by direct interaction with the receptor, but by direct interaction with the nuclear hormone receptor transcriptional coactivator NRC. The encoded protein may function by altering local chromatin structure. [provided by RefSeq, Jul 2008]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
ZNF335
M08952_2.00
Homo sapiens
RGSTGYCYNNNSHDNTGCCTGH

DCAGGCANHDSNNNRGRCASCY
Misc
Kulakovskiy et al.(2013)
ZN335_HUMAN.H11MO.0.A
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Zfp335
M08998_2.00
Mus musculus
RGSTGYCYNNNSHDNTGCCTGH

DCAGGCANHDSNNNRGRCASCY
Misc
Kulakovskiy et al.(2013)
ZN335_MOUSE.H11MO.0.A
0.814 0.970
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000325326 C2H2 ZF 495 517
ENSP00000325326 C2H2 ZF 523 545
ENSP00000325326 C2H2 ZF 562 584
ENSP00000325326 C2H2 ZF 590 612
ENSP00000325326 C2H2 ZF 621 643
ENSP00000325326 C2H2 ZF 678 701
ENSP00000325326 C2H2 ZF 1019 1041
ENSP00000325326 C2H2 ZF 1047 1069
ENSP00000325326 C2H2 ZF 1075 1097
ENSP00000325326 C2H2 ZF 1103 1126

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

23 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ZNF335 Oryctolagus cuniculus ENSOCUG00000016059 I 0.827
ZNF335 Otolemur garnettii ENSOGAG00000015292 I 0.827
ENSPPYG00000011082 Pongo abelii ENSPPYG00000011082 I 0.827
ZNF335 Pan troglodytes ENSPTRG00000023353 I 0.827
ZNF335 Equus caballus ENSECAG00000023647 I 0.827
ZNF335 Gorilla gorilla ENSGGOG00000013550 I 0.827
ZNF335 Callithrix jacchus ENSCJAG00000017215 I 0.827
ENSCSAG00000014693 Chlorocebus sabaeus ENSCSAG00000014693 I 0.827
ZNF335 Cavia porcellus ENSCPOG00000000138 I 0.822
Zfp335 Dipodomys ordii ENSDORG00000007083 I 0.822
ENSSTOG00000006323 Ictidomys tridecemlineatus ENSSTOG00000006323 I 0.822
ZNF335 Pteropus vampyrus ENSPVAG00000000383 I 0.822
ZNF335 Loxodonta africana ENSLAFG00000016142 I 0.822
ZNF335 Tursiops truncatus ENSTTRG00000012103 I 0.821
ZNF335 Myotis lucifugus ENSMLUG00000000282 I 0.820
Myotis_brandtii_ZNF335_10013703 Myotis brandtii Myotis_brandtii_ZNF335_10013703 I 0.820
Zfp335 Rattus norvegicus ENSRNOG00000017290 I 0.819
ENSMPUG00000017610 Mustela putorius furo ENSMPUG00000017610 I 0.818
ENSAMEG00000012733 Ailuropoda melanoleuca ENSAMEG00000012733 I 0.818
ZNF335 Canis familiaris ENSCAFG00000009882 I 0.818
ZNF335 Bos taurus ENSBTAG00000010130 I 0.815
ENSBTAP00000053387-D1 Bos grunniens ENSBTAP00000053387-D1 I 0.815
Zfp335 Mus musculus ENSMUSG00000039834 D 0.814