ZNF879 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000234284 T095457_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene encodes a kruppel-associated box-containing zinc finger protein (KRAB-ZFP). The encoded protein contains an N-terminal kruppel-associated box (KRAB) domain and thirteen C-terminal C2H2-type zinc finger domains. The KRAB-ZFPs represent the largest family of mammalian transcriptional repressors, which function through the recruitment of the nuclear co-factor KRAB-Associated Protein 1 (KAP1), to engage histone modifiers and induce heterochromatin formation. [provided by RefSeq, Jul 2017]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
ZNF879
M07766_2.00
Homo sapiens
DRBTNYRDTRTTDRGTSCATDTATRTTYAN

AWAAHAAWWNTRAAYATAHATGSACYHAAY
ChIP-seq+ChIP-exo
Barazandeh et al.(2018)
ZNF879.RCADE.OriginalMapping
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000414887 C2H2 ZF 204 226
ENSP00000414887 C2H2 ZF 232 254
ENSP00000414887 C2H2 ZF 260 282
ENSP00000414887 C2H2 ZF 288 310
ENSP00000414887 C2H2 ZF 316 338
ENSP00000414887 C2H2 ZF 344 366
ENSP00000414887 C2H2 ZF 372 394
ENSP00000414887 C2H2 ZF 400 422
ENSP00000414887 C2H2 ZF 428 450
ENSP00000414887 C2H2 ZF 456 478
ENSP00000414887 C2H2 ZF 484 506
ENSP00000414887 C2H2 ZF 512 534
ENSP00000414887 C2H2 ZF 540 562

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

23 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ENSAMEG00000009025 Ailuropoda melanoleuca ENSAMEG00000009025 I 0.804
Zfp879 Mus musculus ENSMUSG00000044296 I 0.758
ENSNLEG00000001439 Nomascus leucogenys ENSNLEG00000001439 I 0.827
ZNF879 Oryctolagus cuniculus ENSOCUG00000016395 I 0.798
ZNF879 Otolemur garnettii ENSOGAG00000032797 I 0.805
ENSPANG00000014426 Papio anubis ENSPANG00000014426 I 0.827
ENSPPYG00000029650 Pongo abelii ENSPPYG00000029650 I 0.827
ZNF879 Pan troglodytes ENSPTRG00000041282 I 0.827
Zfp879 Rattus norvegicus ENSRNOG00000030517 I 0.781
ENSP00000341151-D16 Bos grunniens ENSP00000341151-D16 I 0.805
ENSMPUG00000000701 Mustela putorius furo ENSMPUG00000000701 I 0.804
ZNF879 Macaca mulatta ENSMMUG00000002484 I 0.827
ZNF879 Loxodonta africana ENSLAFG00000018662 I 0.799
ZNF879 Canis familiaris ENSCAFG00000030461 I 0.800
ZNF879 Callithrix jacchus ENSCJAG00000018904 I 0.823
ENSCSAG00000008491 Chlorocebus sabaeus ENSCSAG00000008491 I 0.827
ZNF354C Dasypus novemcinctus ENSDNOG00000011675 I 0.795
ZNF879 Equus caballus ENSECAG00000023471 I 0.809
ZNF879 Erinaceus europaeus ENSEEUG00000011407 I 0.784
ZNF879 Echinops telfairi ENSETEG00000004774 I 0.790
ZNF879 Felis catus ENSFCAG00000025356 I 0.805
ZNF879 Gorilla gorilla ENSGGOG00000023048 I 0.827
ENSP00000414887 Macaca fascicularis ENSP00000414887 I 0.827