ZNF674 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000251192 T095470_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene encodes a zinc finger protein with an N-terminal Kruppel-associated box-containing (KRAB) domain and 11 Kruppel-type C2H2 zinc finger domains. Like other zinc finger proteins, this gene may function as a transcription factor. This gene resides on an area of chromosome X that has been implicated in nonsyndromic X-linked cognitive disabilities. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2017]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
ZNF674
M07771_2.00
Homo sapiens
BYBTGGYGCYCC

GGRGCRCCAVRV
ChIP-seq+ChIP-exo
Barazandeh et al.(2018)
ZNF674.RCADE.OriginalMapping
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000428248 C2H2 ZF 218 240
ENSP00000428248 C2H2 ZF 246 268
ENSP00000428248 C2H2 ZF 274 296
ENSP00000428248 C2H2 ZF 302 324
ENSP00000428248 C2H2 ZF 379 401
ENSP00000428248 C2H2 ZF 407 429
ENSP00000428248 C2H2 ZF 435 457
ENSP00000428248 C2H2 ZF 463 485
ENSP00000428248 C2H2 ZF 491 513
ENSP00000428248 C2H2 ZF 519 541
ENSP00000428248 C2H2 ZF 547 569
ENSP00000429148 C2H2 ZF 224 246
ENSP00000429148 C2H2 ZF 252 274
ENSP00000429148 C2H2 ZF 280 302
ENSP00000429148 C2H2 ZF 308 330
ENSP00000429148 C2H2 ZF 385 407
ENSP00000429148 C2H2 ZF 413 435
ENSP00000429148 C2H2 ZF 441 463
ENSP00000429148 C2H2 ZF 469 491
ENSP00000429148 C2H2 ZF 497 519
ENSP00000429148 C2H2 ZF 525 547
ENSP00000429148 C2H2 ZF 553 575

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

17 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ENSBTAP00000035023-D42 Bos grunniens ENSBTAP00000035023-D42 I 0.802
ENSCSAG00000019562 Chlorocebus sabaeus ENSCSAG00000019562 I 0.822
ENSECAG00000018635 Equus caballus ENSECAG00000018635 I 0.797
ENSMPUG00000012937 Mustela putorius furo ENSMPUG00000012937 I 0.802
ENSNLEG00000002837 Nomascus leucogenys ENSNLEG00000002837 I 0.826
ENSPANG00000017370 Papio anubis ENSPANG00000017370 I 0.820
ENSPPYG00000020276 Pongo abelii ENSPPYG00000020276 I 0.826
ZNF674 Sus scrofa ENSSSCG00000012264 I 0.760
ZNF674 Pan troglodytes ENSPTRG00000021829 I 0.825
ZNF674 Tursiops truncatus ENSTTRG00000009837 I 0.809
ZNF674 Macaca mulatta ENSMMUG00000002292 I 0.820
ZNF674 Gorilla gorilla ENSGGOG00000013207 I 0.817
ZNF674 Dasypus novemcinctus ENSDNOG00000045857 I 0.786
ZNF674 Callithrix jacchus ENSCJAG00000011965 I 0.774
ZNF674 Canis familiaris ENSCAFG00000014732 I 0.799
ZNF674 Bos taurus ENSBTAG00000002956 I 0.801