Zbtb49 (Mus musculus)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSMUSG00000029127 T101080_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and transcription coactivator binding activity. Predicted to be involved in negative regulation of cell population proliferation; positive regulation of transcription by RNA polymerase II; and regulation of cell cycle. Predicted to be located in cytosol; microtubule cytoskeleton; and nucleus. Predicted to be active in nucleoplasm. Is expressed in bladder; male associated reproductive structure; testis; ureter; and urethra of male. Orthologous to human ZBTB49 (zinc finger and BTB domain containing 49). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
ZBTB49
M02901_2.00
Homo sapiens
TTYYGCYTGRCVBGTCA

TGACVBGYCARGCRRAA
SELEX
Jolma et al.(2013)
ZBTB49_1
0.810 0.957
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000092429 C2H2 ZF 386 408
ENSMUSP00000092429 C2H2 ZF 414 436
ENSMUSP00000092429 C2H2 ZF 442 464
ENSMUSP00000092429 C2H2 ZF 470 492
ENSMUSP00000092429 C2H2 ZF 498 520
ENSMUSP00000092429 C2H2 ZF 526 548
ENSMUSP00000092429 C2H2 ZF 554 576
ENSMUSP00000109748 C2H2 ZF 386 408
ENSMUSP00000114955 C2H2 ZF 11 33
ENSMUSP00000114955 C2H2 ZF 39 61
ENSMUSP00000117174 C2H2 ZF 386 408
ENSMUSP00000122109 C2H2 ZF 386 408

Links

Other C2H2 ZF family TFs
Other Mus musculus TFs

Invalid Input OrderBy

50 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action