Zbtb45 (Mus musculus)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSMUSG00000049600 T101249_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within nervous system development. Predicted to be located in nucleus. Predicted to be active in nucleoplasm. Is expressed in 2-cell stage embryo; 4-cell stage embryo; and forebrain. Orthologous to human ZBTB45 (zinc finger and BTB domain containing 45). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ZBTB45
M04433_2.00 		Homo sapiens
BMTATAGGBRN
NYVCCTATAKV		 SELEX
Yin et al.(2017)
ZBTB45_eDBD_HT-SELEX 		0.827 1.000
ZBTB45
M04434_2.00 		Homo sapiens
BVTATASGBGN
NCVCSTATABV		 SELEX
Yin et al.(2017)
ZBTB45_eDBD_Methyl-HT-SELEX 		0.827 1.000
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000056086 C2H2 ZF 412 434
ENSMUSP00000056086 C2H2 ZF 440 462
ENSMUSP00000056086 C2H2 ZF 468 490
ENSMUSP00000056086 C2H2 ZF 496 517
ENSMUSP00000130439 C2H2 ZF 412 434
ENSMUSP00000130439 C2H2 ZF 440 462
ENSMUSP00000130439 C2H2 ZF 468 490
ENSMUSP00000130439 C2H2 ZF 496 517

Links

Other C2H2 ZF family TFs
Other Mus musculus TFs

Invalid Input OrderBy

25 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action