peb (Drosophila melanogaster)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 FBgn0003053 T114406_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including cell morphogenesis involved in neuron differentiation; embryonic development via the syncytial blastoderm; and positive regulation of cell-cell adhesion. Located in nucleus and polytene chromosome. Is expressed in several structures, including ectoderm anlage; extended germ band embryo; germ layer; peripheral nervous system; and presumptive embryonic/larval system. Orthologous to human RREB1 (ras responsive element binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
peb
M03582_2.00		 Drosophila melanogaster
YGGWCCA
TGGWCCR		 SELEX
Ming et al.(2013)
CB1		 (Direct) (Direct)
peb
M03583_2.00		 Drosophila melanogaster
GGATGCTGYK
MRCAGCATCC		 SELEX
Ming et al.(2013)
CB2		 (Direct) (Direct)
peb
M06067_2.00		 Drosophila melanogaster
KGATGCT
AGCATCM		 B1H
Zhu et al.(2011)
peb-F1-3_SANGER_2.5_FBgn0003053		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
FBpp0070648 C2H2 ZF 250 272
FBpp0070648 C2H2 ZF 282 304
FBpp0070648 C2H2 ZF 310 332
FBpp0070648 C2H2 ZF 709 731
FBpp0070648 C2H2 ZF 741 763
FBpp0070648 C2H2 ZF 769 792
FBpp0070648 C2H2 ZF 1705 1726
FBpp0070648 C2H2 ZF 1732 1754
FBpp0099653 C2H2 ZF 250 272
FBpp0099653 C2H2 ZF 282 304
FBpp0099653 C2H2 ZF 310 332
FBpp0099653 C2H2 ZF 709 731
FBpp0099653 C2H2 ZF 741 763
FBpp0099653 C2H2 ZF 769 792
FBpp0099653 C2H2 ZF 1705 1726
FBpp0099653 C2H2 ZF 1732 1754

Links

Other C2H2 ZF family TFs
Other Drosophila melanogaster TFs

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11 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action