Trl (Drosophila melanogaster)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 FBgn0013263 T114434_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; POZ domain binding activity; and protein dimerization activity. Involved in several processes, including chromatin organization; gamete generation; and regulation of transcription, DNA-templated. Located in chromosome and nucleus. Part of protein-containing complex. Is expressed in several structures, including embryonic/larval muscle system; embryonic/larval nervous system; extended germ band embryo; eye; and gut section. Orthologous to human BTBD18 (BTB domain containing 18). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Trl
M03679_2.00		 Drosophila melanogaster
MCTCTCTCCC
GGGAGAGAGK		 SELEX
Nitta et al.(2015)
Trl_1		 (Direct) (Direct)
Trl
M06113_2.00		 Drosophila melanogaster
YBDCTCTCBN
NVGAGAGHVR		 B1H
Zhu et al.(2011)
Trl_FlyReg_FBgn0013263		 (Direct) (Direct)
Trl
M07541_2.00		 Drosophila melanogaster
YBDCTCTCBN
NVGAGAGHVR		 DNaseI footprinting
Mathelier et al.(2014)
MA0205.1		 (Direct) (Direct)
Trl
M10379_2.00		 Drosophila melanogaster Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
I$GAGAFACTOR_Q6		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
FBpp0089411 C2H2 ZF 344 366
FBpp0089415 C2H2 ZF 344 366
FBpp0099867 C2H2 ZF 27 48
FBpp0099867 C2H2 ZF 344 366
FBpp0305260 C2H2 ZF 27 48
FBpp0305260 C2H2 ZF 344 366

Links

Other C2H2 ZF family TFs
Other Drosophila melanogaster TFs

Invalid Input OrderBy

2 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action