snai-1 (Caenorhabditis elegans)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 WBGene00019299 T131632_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in PHAL; PHAR; PHBL; PHBR; and amphid neurons. Human ortholog(s) of this gene implicated in Waardenburg syndrome type 2D and piebaldism. Orthologous to several human genes including SNAI1 (snail family transcriptional repressor 1) and SNAI2 (snail family transcriptional repressor 2). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
snai-1
M00642_2.00		 Caenorhabditis elegans
CACCTGT
ACAGGTG		 PBM
Narasimhan et al.(2015)
pTH10802		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00642_2.00 C2H2 ZF 41 63
M00642_2.00 C2H2 ZF 70 92
M00642_2.00 C2H2 ZF 96 118
M00642_2.00 C2H2 ZF 124 146
M00642_2.00 C2H2 ZF 152 172

DNA Binding Domains

Protein ID Domain From To Sequence
K02D7.2 C2H2 ZF 41 63
K02D7.2 C2H2 ZF 70 92
K02D7.2 C2H2 ZF 96 118
K02D7.2 C2H2 ZF 124 146
K02D7.2 C2H2 ZF 152 172

Links

Other C2H2 ZF family TFs
Other Caenorhabditis elegans TFs

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1 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action