TF Information

MET32 *(Saccharomyces cerevisiae)* C2H2 ZF
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF00096 (zf-C2H2)	IPR007087	YDR253C	T131831_2.00	Ensembl (2018-Dec-8)	Link out
NCBI Gene Info: Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II-specific DNA-binding transcription factor binding activity; and cis-regulatory region sequence-specific DNA binding activity. Involved in regulation of mitotic cell cycle; regulation of sulfur amino acid metabolic process; and regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
MET32 M00022_2.00	Saccharomyces cerevisiae	NVMGCCACAV	BTGTGGCKBN	PBM Badis et al.(2008) MET32_2153	(Direct)	(Direct)
MET32 M01528_2.00	Saccharomyces cerevisiae	MGCCACAN	NTGTGGCK	PBM Zhu et al.(2009) Met32	(Direct)	(Direct)
MET32 M07452_2.00	Saccharomyces cerevisiae	MGCCACM	KGTGGCK	PBM, CSA and or DIP-chip Mathelier et al.(2014) MA0334.1	(Direct)	(Direct)
MET32 M08518_2.00	Saccharomyces cerevisiae	VHKCCACA	TGTGGMDB	Misc DeBoer et al.(2011) YDR253C_1375	(Direct)	(Direct)
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
MET31 M00040_2.00	Saccharomyces cerevisiae	NNHCACCTMN	NKAGGTGDNN	PBM Badis et al.(2008) MET31_2146	0.773	0.795
MET31 M07470_2.00	Saccharomyces cerevisiae	MGCCACNNH	DNNGTGGCK	PBM, CSA and or DIP-chip Mathelier et al.(2014) MA0333.1	0.773	0.795
MET31 M08543_2.00	Saccharomyces cerevisiae	VCACWVYK	MRBWGTGB	Misc DeBoer et al.(2011) YPL038W_1370	0.773	0.795
MET31 M10402_2.00	Saccharomyces cerevisiae	Transfac license required	Transfac license required	Transfac Matys et al.(2006) F$MET31_01	0.773	0.795
For this family, TFs with SR scores > 0.755* will likely have a similar motif*

Experimental Constructs

Motif ID	Domain	From	To	Sequence
M00022_2.00	C2H2 ZF	51	73	FKCAKCSLEFSRSSDLRRHEKTH
M00022_2.00	C2H2 ZF	80	100	ICPQCGKGFARKDALKRHYDT
M01528_2.00	C2H2 ZF	98	120	FKCAKCSLEFSRSSDLRRHEKTH
M01528_2.00	C2H2 ZF	127	147	ICPQCGKGFARKDALKRHYDT

DNA Binding Domains

Protein ID	Domain	From	To	Sequence
YDR253C	C2H2 ZF	98	120	FKCAKCSLEFSRSSDLRRHEKTH
YDR253C	C2H2 ZF	127	147	ICPQCGKGFARKDALKRHYDT

Links
Other C2H2 ZF family TFs
Other *Saccharomyces cerevisiae* TFs

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30 Related TFs

Name	Species	Gene ID	Motif Evidence	SR Score	Action