MOT3 (Saccharomyces cerevisiae)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 YMR070W T131851_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in negative regulation of ergosterol biosynthetic process; negative regulation of transcription by RNA polymerase II; and positive regulation of transcription by RNA polymerase II. Located in cytosol and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
MOT3
M00912_2.00		 Saccharomyces cerevisiae
NGTGCCTDY
RHAGGCACN		 PBM
Gordan et al.(2011)
Mot3		 (Direct) (Direct)
MOT3
M08417_2.00		 Saccharomyces cerevisiae
TRCCTD
HAGGYA		 ChIP-chip
Mathelier et al.(2014)
MA0340.1		 (Direct) (Direct)
MOT3
M08539_2.00		 Saccharomyces cerevisiae
TRCCTD
HAGGYA		 Misc
DeBoer et al.(2011)
YMR070W_597		 (Direct) (Direct)
MOT3
M10400_2.00		 Saccharomyces cerevisiae Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
F$MOT3_01		 (Direct) (Direct)
MOT3
M10401_2.00		 Saccharomyces cerevisiae Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
F$MOT3_Q2		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00912_2.00 C2H2 ZF 346 368
M00912_2.00 C2H2 ZF 374 397

DNA Binding Domains

Protein ID Domain From To Sequence
YMR070W C2H2 ZF 346 368
YMR070W C2H2 ZF 374 397

Links

Other C2H2 ZF family TFs
Other Saccharomyces cerevisiae TFs

Invalid Input OrderBy

6 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action