|
|
ENSBTAP00000035733-D1
(Bos grunniens)
C2H2 ZF
|
TF Information |
|---|
| Pfam ID |
Interpro ID |
Gene ID |
CIS-BP ID |
Sequence source |
| PF00096 (zf-C2H2) |
IPR007087 |
ENSBTAP00000035733-D1 |
T134639_2.00 |
GigaDB (2015-Oct-22) |
| NCBI Gene Info:This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016] |
Directly determined binding motifs |
|---|
| Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR
Score |
DBD
Identity |
| No direct experiments |
|
|
|
|
|
Motifs from related TFs |
|---|
| Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR
Score |
DBD
Identity |
ZBTB7A
M02914_2.00 |
Homo sapiens |
NRCGACCACCNV |
BNGGTGGTCGYN |
SELEX
Jolma et al.(2013)
ZBTB7A_1
|
0.827
|
1.000
|
ZBTB7A
M04579_2.00 |
Homo sapiens |
DCGACCMCCVH |
DBGGKGGTCGH |
SELEX
Yin et al.(2017)
ZBTB7A_eDBD_HT-SELEX
|
0.827
|
1.000
|
ZBTB7A
M08095_2.00 |
Homo sapiens |
NBSRCTTCCGGNN |
NNCCGGAAGYSVN |
ChIP-seq
Mathelier et al.(2014)
MA0750.2
|
0.827
|
1.000
|
ZBTB7A
M07937_2.00 |
Homo sapiens |
SNVVGMCCCYNNSBS |
SVSNNRGGGKCBBNS |
ChIP-seq
Gerstein et al.(2012)
K562_ZBTB7A_HudsonAlpha
|
0.827
|
1.000
|
ZBTB7A
M08926_2.00 |
Homo sapiens |
VVGMCCCYB |
VRGGGKCBB |
Misc
Kulakovskiy et al.(2013)
ZBT7A_HUMAN.H11MO.0.A
|
0.827
|
1.000
|
Zbtb7a
M08991_2.00 |
Mus musculus |
VVGMCCCYB |
VRGGGKCBB |
Misc
Kulakovskiy et al.(2013)
ZBT7A_MOUSE.H11MO.0.B
|
0.827
|
1.000
|
ZBTB7A
M10273_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$LRF_Q2
|
0.827
|
1.000
|
ZBTB7A
M10274_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$LRF_Q3
|
0.827
|
1.000
|
ZBTB7A
M10275_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$LRF_Q6
|
0.827
|
1.000
|
ZBTB7A
M10276_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$ZBTB7A_02
|
0.827
|
1.000
|
ZBTB7A
M10277_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$ZBTB7A_03
|
0.827
|
1.000
|
ZBTB7A
M04580_2.00 |
Homo sapiens |
DCGACCACCNH |
DNGGTGGTCGH |
SELEX
Yin et al.(2017)
ZBTB7A_eDBD_Methyl-HT-SELEX
|
0.827
|
1.000
|
| For this family, TFs with SR scores > 0.755 will likely have a similar motif |