HHAL006666-PA (Halyomorpha halys)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00096 (zf-C2H2) IPR007087 HHAL006666-PA T144076_2.00 Misc (2018-Jan-19)
NCBI Gene Info:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
HHAL006666-PA C2H2 ZF 61 83
HHAL006666-PA C2H2 ZF 113 137
HHAL006666-PA C2H2 ZF 143 165

Links

Other C2H2 ZF family TFs
Other Halyomorpha halys TFs

13 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
BGIBMGA002238 Bombyx mori BGIBMGA002238 I 0.761
CLEC005464 Cimex lectularius CLEC005464 I 0.777
GB49501 Apis mellifera GB49501 N 0.777
HMEL016959 Heliconius melpomene HMEL016959 I 0.761
ISCW000054 Ixodes scapularis ISCW000054 I 0.781
KGM_06603 Danaus plexippus KGM_06603 I 0.761
LDEC017422 Leptinotarsa decemlineata LDEC017422 I 0.780
MCINX014717 Melitaea cinxia MCINX014717 I 0.761
PHUM127400 Pediculus humanus PHUM127400 I 0.790
RPRC014216 Rhodnius prolixus RPRC014216 N 0.824
SMAR000785 Strigamia maritima SMAR000785 I 0.790
TC010992 Tribolium castaneum TC010992 I 0.780
tetur02g06400 Tetranychus urticae tetur02g06400 I 0.758