Tet1 (Mus musculus)
CxxC

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF02008 (zf-CXXC) IPR002857 ENSMUSG00000047146 T168126_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables methylcytosine dioxygenase activity. Involved in several processes, including dendrite morphogenesis; inner cell mass cell differentiation; and protein O-linked glycosylation. Acts upstream of or within DNA demethylation; regulation of DNA methylation; and regulation of genetic imprinting. Located in nucleus. Is expressed in several structures, including brain; early conceptus; embryo ectoderm; lower urogenital tract; and reproductive system. Orthologous to human TET1 (tet methylcytosine dioxygenase 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
TET1
M01914_2.00 		Homo sapiens
NNHVCGHNN
NNDCGBDNN		 PBM
Weirauch et al.(2014)
pTH9605 		0.881 0.881
XP_001368961.2
M01917_2.00 		Monodelphis domestica
SSGGGGGV
BCCCCCSS		 PBM
Weirauch et al.(2014)
pTH9485 		0.738 0.738
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000059527 CxxC 566 607
ENSMUSP00000133279 CxxC 566 607

Links

Other CxxC family TFs
Other Mus musculus TFs

Invalid Input OrderBy

38 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action