TF Information

ENSP00000366271 *(Macaca fascicularis)* CxxC
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source
PF02008 (zf-CXXC)	IPR002857	ENSP00000366271	T168598_2.00	GigaDB (2015-Oct-22)
NCBI Gene Info: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
No direct experiments
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
KDM2B M01911_2.00	Homo sapiens	NNNNNNCGN	NCGNNNNNN	PBM Weirauch et al.(2014) pTH9191	1.000	1.000
kdm2ba M01909_2.00	Danio rerio	NNNNCGN	NCGNNNN	PBM Weirauch et al.(2014) pTH8577	0.979	0.979
FBXL19 M01916_2.00	Tetraodon nigroviridis	NNNNCGNN	NNCGNNNN	PBM Weirauch et al.(2014) pTH8570	0.894	0.894
A6H8I1_DANRE M01906_2.00	Danio rerio	CGTACGYA	TRCGTACG	PBM Weirauch et al.(2014) pTH9257	0.851	0.851
KDM2A M01915_2.00	Meleagris gallopavo	NNNNYRNNNN	NNNNYRNNNN	PBM Weirauch et al.(2014) pTH9212	0.809	0.809
BGIBMGA012843 M01907_2.00	Bombyx mori	NNCGCGTANVNN	NNBNTACGCGNN	PBM Weirauch et al.(2014) pTH9239	0.766	0.766
kdm2aa M01910_2.00	Danio rerio	NCGNNNNNN	NNNNNNCGN	PBM Weirauch et al.(2014) pTH8585	0.723	0.723
For this family, TFs with SR scores > 0.700* will likely have a similar motif*