|
|
HHAL002628-PA
(Halyomorpha halys)
Forkhead
|
TF Information |
|---|
| Pfam ID |
Interpro ID |
Gene ID |
CIS-BP ID |
Sequence source |
| PF00250 (Forkhead) |
IPR001766 |
HHAL002628-PA |
T189528_2.00 |
Misc (2018-Jan-19) |
| NCBI Gene Info:This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016] |
Directly determined binding motifs |
|---|
| Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR
Score |
DBD
Identity |
| No direct experiments |
|
|
|
|
|
Motifs from related TFs |
|---|
| Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR
Score |
DBD
Identity |
FOXP1
M00836_2.00 |
Homo sapiens |
NRTMAACANN |
NNTGTTKAYN |
PBM
Gabut et al.(2011)
pEX0123
|
0.737
|
0.877
|
FOXP1
M00837_2.00 |
Homo sapiens |
DGTAAACAA |
TTGTTTACH |
PBM
Gabut et al.(2011)
pEX0124
|
0.737
|
0.877
|
FOXP1
M01976_2.00 |
Homo sapiens |
RTAAACAA |
TTGTTTAY |
PBM
Weirauch et al.(2014)
pTH5656
|
0.737
|
0.877
|
Foxp1
M00793_2.00 |
Mus musculus |
NRTMAAYAN |
NTRTTKAYN |
PBM
Weirauch et al.(2013)
pTH3855
|
0.737
|
0.877
|
FOXP1
M04811_2.00 |
Homo sapiens |
NTGTTTRYNRTNNNNNNBNAYRVWMAACAN |
NTGTTKWBYRTNVNNNNNNAYNRYAAACAN |
SELEX
Yin et al.(2017)
FOXP1_eDBD_HT-SELEX
|
0.737
|
0.877
|
FOXP1
M08115_2.00 |
Homo sapiens |
NDGTAAACAVNN |
NNBTGTTTACHN |
ChIP-seq
Mathelier et al.(2014)
MA0481.2
|
0.737
|
0.877
|
FOXP1
M09086_2.00 |
Homo sapiens |
RKAAACAVM |
KBTGTTTMY |
Misc
Kulakovskiy et al.(2013)
FOXP1_HUMAN.H11MO.0.A
|
0.737
|
0.877
|
FOXP1
M09541_2.00 |
Homo sapiens |
NDGTAAACAVNN |
NNBTGTTTACHN |
Misc
Heinz et al.(2010)
H9-FOXP1_GSE31006
|
0.737
|
0.877
|
FOXP1
M10536_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$FOXP1_01
|
0.737
|
0.877
|
FOXP1
M04812_2.00 |
Homo sapiens |
NTGTTTRYBRTNNNNNNBNAYRVWMAACAH |
DTGTTKWBYRTNVNNNNNNAYVRYAAACAN |
SELEX
Yin et al.(2017)
FOXP1_eDBD_Methyl-HT-SELEX
|
0.737
|
0.877
|
Foxp2
M00792_2.00 |
Mus musculus |
RTAAACAD |
HTGTTTAY |
PBM
Weirauch et al.(2013)
pTH1288
|
0.717
|
0.840
|
FOXP2
M05866_2.00 |
Homo sapiens |
RTAAAYAWNN |
NNWTRTTTAY |
SMiLE-seq
Isakova et al.(2017)
FOXP2
|
0.717
|
0.840
|
FOXP2
M08116_2.00 |
Homo sapiens |
NDGTAAACAVN |
NBTGTTTACHN |
ChIP-seq
Mathelier et al.(2014)
MA0593.1
|
0.717
|
0.840
|
FOXP2
M09089_2.00 |
Homo sapiens |
DGTAAACAV |
BTGTTTACH |
Misc
Kulakovskiy et al.(2013)
FOXP2_HUMAN.H11MO.0.C
|
0.717
|
0.840
|
Foxp2
M09101_2.00 |
Mus musculus |
NGTAAACAN |
NTGTTTACN |
Misc
Kulakovskiy et al.(2013)
FOXP2_MOUSE.H11MO.0.A
|
0.717
|
0.840
|
FoxP
M03753_2.00 |
Drosophila melanogaster |
AAACAACAACAA |
TTGTTGTTGTTT |
SELEX
Nitta et al.(2015)
CG16899_1
|
0.711
|
0.815
|
FoxP
M06201_2.00 |
Drosophila melanogaster |
VRTAAACAA |
TTGTTTAYB |
B1H
Zhu et al.(2011)
CG16899_SANGER_5_FBgn0037735
|
0.711
|
0.815
|
FoxP
M06202_2.00 |
Drosophila melanogaster |
VNNVBBAAAAAAAD |
HTTTTTTTVVBNNB |
B1H
Zhu et al.(2011)
CG2052_SANGER_2.5_FBgn0039905
|
0.711
|
0.815
|
FoxP
M06203_2.00 |
Drosophila melanogaster |
NNNNNRAAAAAAWNN |
NNWTTTTTTYNNNNN |
B1H
Zhu et al.(2011)
CG2052_SOLEXA_2.5_FBgn0039905
|
0.711
|
0.815
|
| For this family, TFs with SR scores > 0.664 will likely have a similar motif |