TF Information

HHAL007247-PA *(Halyomorpha halys)* GATA
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source
PF00320 (GATA)	IPR000679	HHAL007247-PA	T196880_2.00	Misc (2018-Jan-19)
NCBI Gene Info: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
No direct experiments
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
GATAe M03761_2.00	Drosophila melanogaster	VHGATAAS	STTATCDB	SELEX Nitta et al.(2015) GATAe_1	0.836	0.686
GATAe M03762_2.00	Drosophila melanogaster	HGATAACNNNGTTATCD	HGATAACNNNGTTATCD	SELEX Nitta et al.(2015) GATAe_2	0.836	0.686
GATAe M03763_2.00	Drosophila melanogaster	HGATAAGNNNCTTATCD	HGATAAGNNNCTTATCD	SELEX Nitta et al.(2015) GATAe_3	0.836	0.686
GATAe M06208_2.00	Drosophila melanogaster	WGATAAG	CTTATCW	B1H Zhu et al.(2011) GATAe_SANGER_5_FBgn0038391	0.836	0.686
nit-2 M02017_2.00	Neurospora crassa	NNGATHNN	NNDATCNN	PBM Weirauch et al.(2014) pTH8624	0.823	0.686
nit-2 M10601_2.00	Neurospora crassa	DHGATA	TATCDH	Transfac Matys et al.(2006) F$NIT2_01	0.823	0.686
For this family, TFs with SR scores > 0.802* will likely have a similar motif*