SIX4 (Loxodonta africana)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSLAFG00000021577 T211064_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Six4
M00461_2.00
Mus musculus
NNKABMHNN

NNDKVTMNN
PBM
Berger et al.(2008)
Six4_2860
0.867 1.000
SIX4
M04939_2.00
Homo sapiens
NVYGATACVB

VBGTATCRBN
SELEX
Yin et al.(2017)
SIX4_eDBD_HT-SELEX
0.867 1.000
Six4
M09198_2.00
Mus musculus
DGDAABHNSASNNN

NNNSTSNDVTTHCH
Misc
Kulakovskiy et al.(2013)
SIX4_MOUSE.H11MO.0.C
0.867 1.000
SIX4
M10646_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$SIX4_Q3
0.867 1.000
SIX4
M04940_2.00
Homo sapiens
NBGTAWCRHN

NDYGWTACVN
SELEX
Yin et al.(2017)
SIX4_eDBD_Methyl-HT-SELEX
0.867 1.000
Six4
M00563_2.00
Drosophila melanogaster
NNDANMHNN

NNDKNTHNN
PBM
Busser et al.(2012a)
Six4
0.827 0.792
Six4
M06530_2.00
Drosophila melanogaster
TGABAC

GTVTCA
B1H
Mathelier et al.(2014)
MA0204.1
0.827 0.792
Six4
M06334_2.00
Drosophila melanogaster
WDDTGABAC

GTVTCAHHW
B1H
Zhu et al.(2011)
Six4_Cell_FBgn0027364
0.827 0.792
Six4
M06335_2.00
Drosophila melanogaster
NTGAKACB

VGTMTCAN
B1H
Zhu et al.(2011)
Six4_SOLEXA_2_FBgn0027364
0.827 0.792
Six4
M06336_2.00
Drosophila melanogaster
NNNTGABA

TVTCANNN
B1H
Zhu et al.(2011)
Six4_SOLEXA_FBgn0027364
0.827 0.792
SIX5
M08208_2.00
Homo sapiens
GARWTGTAGT

ACTACAWYTC
ChIP-seq
Contrino et al.(2012)
Mv121
0.826 0.774
SIX5
M08209_2.00
Homo sapiens
GGAGTTGT

ACAACTCC
ChIP-seq
Contrino et al.(2012)
Mv123
0.826 0.774
SIX5
M10738_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$SIX5_01
0.826 0.774
SIX5
M10739_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$SIX5_02
0.826 0.774
Six2
M00425_2.00
Mus musculus
NNAYMYNN

NNRKRTNN
PBM
Berger et al.(2008)
Six2_2307
0.708 0.736
Six1
M00512_2.00
Mus musculus
NNDATMYNNN

NNNRKATHNN
PBM
Berger et al.(2008)
Six1_0935
0.708 0.736
SIX1
M05094_2.00
Homo sapiens
NNYGATACVB

VBGTATCRNN
SELEX
Yin et al.(2017)
SIX1_eDBD_HT-SELEX
0.708 0.736
SIX1
M05096_2.00
Homo sapiens
NNYGATAYVB

VBRTATCRNN
SELEX
Yin et al.(2017)
SIX1_FL_HT-SELEX
0.708 0.736
SIX2
M05285_2.00
Homo sapiens
NNYGATACSB

VSGTATCRNN
SELEX
Yin et al.(2017)
SIX2_eDBD_HT-SELEX
0.708 0.736
SIX2
M05287_2.00
Homo sapiens
NSGTRWCRYN

NRYGWYACSN
SELEX
Yin et al.(2017)
SIX2_FL_HT-SELEX
0.708 0.736
SIX1
M08130_2.00
Homo sapiens
GWAACCTGANM

KNTCAGGTTWC
ChIP-seq
Mathelier et al.(2014)
MA1118.1
0.708 0.736
SIX2
M08133_2.00
Homo sapiens
NNNTGWAACCTGAKMH

DKMTCAGGTTWCANNN
ChIP-seq
Mathelier et al.(2014)
MA1119.1
0.708 0.736
SIX1
M09142_2.00
Homo sapiens
DGWAAYHTGABMYN

NRKVTCADRTTWCH
Misc
Kulakovskiy et al.(2013)
SIX1_HUMAN.H11MO.0.A
0.708 0.736
SIX2
M09157_2.00
Homo sapiens
DGWAAYHHGABMH

DKVTCDDRTTWCH
Misc
Kulakovskiy et al.(2013)
SIX2_HUMAN.H11MO.0.A
0.708 0.736
Six2
M09185_2.00
Mus musculus
DGWAAYHYRABMYB

VRKVTYRDRTTWCH
Misc
Kulakovskiy et al.(2013)
SIX2_MOUSE.H11MO.0.A
0.708 0.736
Six1
M09579_2.00
Mus musculus
GWAAYHTGABMH

DKVTCADRTTWC
Misc
Heinz et al.(2010)
Myoblast-Six1_GSE20150
0.708 0.736
SIX1
M10684_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$SIX1_Q3_01
0.708 0.736
SIX1
M10685_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$SIX1_Q3
0.708 0.736
SIX1
M05095_2.00
Homo sapiens
NNYGATABNB

VNVTATCRNN
SELEX
Yin et al.(2017)
SIX1_eDBD_Methyl-HT-SELEX
0.708 0.736
SIX1
M05097_2.00
Homo sapiens
NNYGATAYSB

VSRTATCRNN
SELEX
Yin et al.(2017)
SIX1_FL_Methyl-HT-SELEX
0.708 0.736
SIX2
M05286_2.00
Homo sapiens
NBRTATCRNN

NNYGATAYVN
SELEX
Yin et al.(2017)
SIX2_eDBD_Methyl-HT-SELEX
0.708 0.736
SIX2
M05288_2.00
Homo sapiens
VBRTAWCRNN

NNYGWTAYVB
SELEX
Yin et al.(2017)
SIX2_FL_Methyl-HT-SELEX
0.708 0.736
so
M02117_2.00
Drosophila melanogaster
NDATMYNNN

NNNRKATHN
PBM
Weirauch et al.(2014)
pTH5690
0.708 0.717
so
M03800_2.00
Drosophila melanogaster
NYGATAYB

VRTATCRN
SELEX
Nitta et al.(2015)
so_1
0.708 0.717
so
M03801_2.00
Drosophila melanogaster
YKATAYNNNYGATAY

RTATCRNNNRTATMR
SELEX
Nitta et al.(2015)
so_2
0.708 0.717
so
M03802_2.00
Drosophila melanogaster
YGATACGTATCR

YGATACGTATCR
SELEX
Nitta et al.(2015)
so_3
0.708 0.717
so
M03803_2.00
Drosophila melanogaster
RTATCRYGATAC

GTATCRYGATAY
SELEX
Nitta et al.(2015)
so_4
0.708 0.717
so
M06497_2.00
Drosophila melanogaster
TGATAC

GTATCA
B1H
Mathelier et al.(2014)
MA0246.1
0.708 0.717
so
M06268_2.00
Drosophila melanogaster
NRTGATA

TATCAYN
B1H
Zhu et al.(2011)
So_Cell_FBgn0003460
0.708 0.717
so
M06269_2.00
Drosophila melanogaster
NNNTGATA

TATCANNN
B1H
Zhu et al.(2011)
So_SOLEXA_FBgn0003460
0.708 0.717
ceh-34
M00672_2.00
Caenorhabditis elegans
NNNRDAWNNN

NNNWTHYNNN
PBM
Narasimhan et al.(2015)
pTH9708
0.634 0.604
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSLAFP00000016495 Homeodomain 105 157

Links

Other Homeodomain family TFs
Other Loxodonta africana TFs

542 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
THAP5 Anolis carolinensis ENSACAG00000001543 N 0.000
ENSPANG00000006063 Papio anubis ENSPANG00000006063 N 0.000
ENSPSIG00000007406 Pelodiscus sinensis ENSPSIG00000007406 N 0.000
THAP5 Pan troglodytes ENSPTRG00000019592 N 0.000
ENSSHAG00000012010 Sarcophilus harrisii ENSSHAG00000012010 N 0.000
ENSSSCG00000026122 Sus scrofa ENSSSCG00000026122 N 0.000
ENSSTOG00000022120 Ictidomys tridecemlineatus ENSSTOG00000022120 N 0.000
THAP5 Taeniopygia guttata ENSTGUG00000005607 N 0.000
Aan_R002084 Calypte anna Aan_R002084 N 0.000
Alligator_sinensis_CCG010116.1 Alligator sinensis Alligator_sinensis_CCG010116.1 N 0.000
Brh_R008791 Buceros rhinoceros Brh_R008791 N 0.000
Cmyd_10009233 Chelonia mydas Cmyd_10009233 N 0.000
ENSP00000400500-D1 Bos grunniens ENSP00000400500-D1 N 0.000
ENSP00000400500 Macaca fascicularis ENSP00000400500 N 0.000
Gfo_R011510 Geospiza fortis Gfo_R011510 N 0.000
Myotis_brandtii_THAP5_10020088 Myotis brandtii Myotis_brandtii_THAP5_10020088 N 0.000
Ogr11944 Ophisaurus gracilis Ogr11944 N 0.000
ENSOCUG00000024652 Oryctolagus cuniculus ENSOCUG00000024652 N 0.000
ENSOARG00000003531 Ovis aries ENSOARG00000003531 N 0.000
ENSNLEG00000008290 Nomascus leucogenys ENSNLEG00000008290 N 0.000
ENSAMEG00000018137 Ailuropoda melanoleuca ENSAMEG00000018137 N 0.000
THAP5 Bos taurus ENSBTAG00000021869 N 0.000
THAP5 Canis familiaris ENSCAFG00000003290 N 0.000
THAP5 Callithrix jacchus ENSCJAG00000016711 N 0.000
ENSCPOG00000001682 Cavia porcellus ENSCPOG00000001682 N 0.000
ENSCSAG00000011171 Chlorocebus sabaeus ENSCSAG00000011171 N 0.000
ENSDNOG00000033245 Dasypus novemcinctus ENSDNOG00000033245 N 0.000
ENSFALG00000009293 Ficedula albicollis ENSFALG00000009293 N 0.000
THAP5 Felis catus ENSFCAG00000030075 N 0.000
THAP5 Homo sapiens ENSG00000177683 N 0.000
THAP5 Gallus gallus ENSGALG00000009494 N 0.000
ENSLACG00000010000 Latimeria chalumnae ENSLACG00000010000 N 0.000
THAP5 Loxodonta africana ENSLAFG00000017693 N 0.000
THAP5 Myotis lucifugus ENSMLUG00000015130 N 0.000
THAP5 Monodelphis domestica ENSMODG00000024563 N 0.000
ENSMPUG00000007795 Mustela putorius furo ENSMPUG00000007795 N 0.000
Pvit_15103 Pogona vitticeps Pvit_15103 N 0.000