Hdx (Mus musculus)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSMUSG00000034551 T212477_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in enteric nervous system. Orthologous to human HDX (highly divergent homeobox). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Hdx
M00463_2.00
Mus musculus
HNWYHNN

NNDRWND
PBM
Berger et al.(2008)
Hdx_3845
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
HDX
M01246_2.00
Homo sapiens
HNNNNNN

NNNNNND
PBM
Lambert et al.(2019)
pTH11271
0.867 0.991
For this family, TFs with SR scores > 0.599 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00463_2.00 Homeodomain 2 60
M00463_2.00 Homeodomain 439 498

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000043482 Homeodomain 381 440
ENSMUSP00000109049 Homeodomain 2 60
ENSMUSP00000109049 Homeodomain 439 498

Links

Other Homeodomain family TFs
Other Mus musculus TFs

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61 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action