|
HHAL005727-PA
(Halyomorpha halys)
Homeodomain
|
TF Information |
Pfam ID |
Interpro ID |
Gene ID |
CIS-BP ID |
Sequence source |
PF00046 (Homeobox) |
IPR001356 |
HHAL005727-PA |
T229849_2.00 |
Misc (2018-Jan-19) |
NCBI Gene Info:This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016] |
Directly determined binding motifs |
Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR Score |
DBD Identity |
No direct experiments |
|
|
|
|
|
Motifs from related TFs |
Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR Score |
DBD Identity |
exd
M06487_2.00 |
Drosophila melanogaster |
YRTCAAAN |
NTTTGAYR |
B1H
Mathelier et al.(2014)
MA0222.1
|
0.865
|
0.982
|
exd
M06243_2.00 |
Drosophila melanogaster |
YRTCAAAN |
NTTTGAYR |
B1H
Zhu et al.(2011)
Exd_Cell_FBgn0000611
|
0.865
|
0.982
|
exd
M06244_2.00 |
Drosophila melanogaster |
NWRNWYNAAA |
TTTNRWNYWN |
B1H
Zhu et al.(2011)
exd_FlyReg_FBgn0000611
|
0.865
|
0.982
|
exd
M06245_2.00 |
Drosophila melanogaster |
NDTGAYRW |
WYRTCAHN |
B1H
Zhu et al.(2011)
exd_SOLEXA_2_FBgn0000611
|
0.865
|
0.982
|
exd
M06246_2.00 |
Drosophila melanogaster |
NNDTGAYR |
YRTCAHNN |
B1H
Zhu et al.(2011)
Exd_SOLEXA_FBgn0000611
|
0.865
|
0.982
|
Pbx3
M09205_2.00 |
Mus musculus |
BBBTGATTGRYNDN |
NHNRYCAATCAVVV |
Misc
Kulakovskiy et al.(2013)
PBX3_MOUSE.H11MO.0.A
|
0.822
|
0.965
|
Pbx1
M00513_2.00 |
Mus musculus |
NNDKANNNN |
NNNNTMHNN |
PBM
Berger et al.(2008)
Pbx1_3203
|
0.820
|
0.930
|
PBX1
M05362_2.00 |
Homo sapiens |
NTGATKGAYR |
YRTCMATCAN |
SELEX
Yin et al.(2017)
PBX1_eDBD_HT-SELEX
|
0.820
|
0.930
|
PBX1
M05364_2.00 |
Homo sapiens |
DTGMTKGRYN |
NRYCMAKCAH |
SELEX
Yin et al.(2017)
PBX1_FL_HT-SELEX
|
0.820
|
0.930
|
PBX1
M02685_2.00 |
Homo sapiens |
WWTGATTGATND |
HNATCAATCAWW |
SELEX
Mathelier et al.(2014)
MA0070.1
|
0.820
|
0.930
|
PBX2
M08134_2.00 |
Homo sapiens |
NWGAKTGACABN |
NVTGTCAMTCWN |
ChIP-seq
Mathelier et al.(2014)
MA1113.1
|
0.820
|
0.930
|
PBX1
M09164_2.00 |
Homo sapiens |
DGABTGRCRG |
CYGYCAVTCH |
Misc
Kulakovskiy et al.(2013)
PBX1_HUMAN.H11MO.0.A
|
0.820
|
0.930
|
PBX2
M09165_2.00 |
Homo sapiens |
KRVHKTGATTGAWKN |
NMWTCAATCAMDBYM |
Misc
Kulakovskiy et al.(2013)
PBX2_HUMAN.H11MO.0.C
|
0.820
|
0.930
|
Pbx2
M09199_2.00 |
Mus musculus |
KRVHKTGATTGAWKN |
NMWTCAATCAMDBYM |
Misc
Kulakovskiy et al.(2013)
PBX2_MOUSE.H11MO.0.C
|
0.820
|
0.930
|
PBX1
M09561_2.00 |
Homo sapiens |
TGABTGACAGSC |
GSCTGTCAVTCA |
Misc
Heinz et al.(2010)
MCF7-PBX1_GSE28007
|
0.820
|
0.930
|
PBX1
M10748_2.00 |
Homo sapiens |
WTKATTRDT |
AHYAATMAW |
Transfac
Matys et al.(2006)
V$PBX1_01
|
0.820
|
0.930
|
PBX1
M10749_2.00 |
Homo sapiens |
DNHTTGATTGATKDB |
VHMATCAATCAADNH |
Transfac
Matys et al.(2006)
V$PBX1_02
|
0.820
|
0.930
|
PBX1
M10750_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$PBX1_03
|
0.820
|
0.930
|
PBX1
M10751_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$PBX1_05
|
0.820
|
0.930
|
PBX1
M10752_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$PBX1_10
|
0.820
|
0.930
|
PBX1
M10753_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$PBX1_Q3
|
0.820
|
0.930
|
PBX1
M05363_2.00 |
Homo sapiens |
DTGAKKGAYG |
CRTCMMTCAH |
SELEX
Yin et al.(2017)
PBX1_eDBD_Methyl-HT-SELEX
|
0.820
|
0.930
|
PBX1
M05365_2.00 |
Homo sapiens |
MRTCAATCMH |
DKGATTGAYK |
SELEX
Yin et al.(2017)
PBX1_FL_Methyl-HT-SELEX
|
0.820
|
0.930
|
pbx4
M02110_2.00 |
Tetraodon nigroviridis |
TTGAYGDV |
BHCRTCAA |
PBM
Weirauch et al.(2014)
pTH6425
|
0.820
|
0.912
|
PBX4
M00277_2.00 |
Homo sapiens |
NNDDWHDNNN |
NNNHDWHHNN |
PBM
Barrera et al.(2016)
PBX4_REF
|
0.769
|
0.877
|
PBX4
M10649_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$PBX4_01
|
0.769
|
0.877
|
CBG10835
M01243_2.00 |
Caenorhabditis briggsae |
NNTKAYDNN |
NNHRTMANN |
PBM
Lambert et al.(2019)
pTH11444
|
0.646
|
0.544
|
PBX4
M00276_2.00 |
Homo sapiens |
NYTAATTADNN |
NNHTAATTARN |
PBM
Barrera et al.(2016)
PBX4_R215Q
|
0.630
|
0.860
|
For this family, TFs with SR scores > 0.599 will likely have a similar motif |