|
HHAL007381-PA
(Halyomorpha halys)
Homeodomain
|
TF Information |
Pfam ID |
Interpro ID |
Gene ID |
CIS-BP ID |
Sequence source |
PF00046 (Homeobox) |
IPR001356 |
HHAL007381-PA |
T229853_2.00 |
Misc (2018-Jan-19) |
NCBI Gene Info:This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016] |
Directly determined binding motifs |
Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR Score |
DBD Identity |
No direct experiments |
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Motifs from related TFs |
Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR Score |
DBD Identity |
ara
M06518_2.00 |
Drosophila melanogaster |
WWACA |
TGTWW |
B1H
Mathelier et al.(2014)
MA0210.1
|
0.867
|
1.000
|
ara
M06313_2.00 |
Drosophila melanogaster |
TGTWWWNN |
NNWWWACA |
B1H
Zhu et al.(2011)
Ara_Cell_FBgn0015904
|
0.867
|
1.000
|
ara
M06314_2.00 |
Drosophila melanogaster |
DWWACA |
TGTWWH |
B1H
Zhu et al.(2011)
Ara_SOLEXA_FBgn0015904
|
0.867
|
1.000
|
caup
M06519_2.00 |
Drosophila melanogaster |
WAACA |
TGTTW |
B1H
Mathelier et al.(2014)
MA0217.1
|
0.858
|
0.947
|
caup
M06315_2.00 |
Drosophila melanogaster |
HWDWAACA |
TGTTWHWD |
B1H
Zhu et al.(2011)
Caup_Cell_FBgn0015919
|
0.858
|
0.947
|
caup
M06316_2.00 |
Drosophila melanogaster |
NDDACA |
TGTHHN |
B1H
Zhu et al.(2011)
Caup_SOLEXA_FBgn0015919
|
0.858
|
0.947
|
Irx6
M00456_2.00 |
Mus musculus |
NNDAHWN |
NWDTHNN |
PBM
Berger et al.(2008)
Irx6_2623
|
0.832
|
0.930
|
Irx2
M00386_2.00 |
Mus musculus |
NNDACAHNN |
NNDTGTHNN |
PBM
Berger et al.(2008)
Irx2_0900
|
0.815
|
0.930
|
Irx5
M00455_2.00 |
Mus musculus |
NNNDACAHN |
NDTGTHNNN |
PBM
Berger et al.(2008)
Irx5_2385
|
0.815
|
0.930
|
IRX2
M03212_2.00 |
Homo sapiens |
NDACAYRACAHN |
NDTGTYRTGTHN |
SELEX
Jolma et al.(2013)
IRX2_1
|
0.815
|
0.930
|
IRX5
M03222_2.00 |
Homo sapiens |
NDACAYRACAHN |
NDTGTYRTGTHN |
SELEX
Jolma et al.(2013)
IRX5_1
|
0.815
|
0.930
|
IRX5
M05315_2.00 |
Homo sapiens |
NBDTGTHNDACAYVN |
NBRTGTHNDACAHVN |
SELEX
Yin et al.(2017)
IRX5_eDBD_HT-SELEX
|
0.815
|
0.930
|
IRX5
M05316_2.00 |
Homo sapiens |
WYRYGHHNHAYRYRY |
RYRYRTDNDDCRYRW |
SELEX
Yin et al.(2017)
IRX5_eDBD_Methyl-HT-SELEX
|
0.815
|
0.930
|
Irx4
M00416_2.00 |
Mus musculus |
NNNDAMAH |
DTKTHNNN |
PBM
Berger et al.(2008)
Irx4_2242
|
0.788
|
0.912
|
For this family, TFs with SR scores > 0.599 will likely have a similar motif |