pax4 (Danio rerio)
Homeodomain,Paired box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox)
PF00292 (PAX) 		IPR001356
IPR001523 		ENSDARG00000021336 T237306_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within endocrine pancreas development; glucose homeostasis; and pancreas regeneration. Predicted to be located in nucleus. Is expressed in endocrine system and gut. Human ortholog(s) of this gene implicated in diabetic ketoacidosis; maturity-onset diabetes of the young type 9; type 1 diabetes mellitus; and type 2 diabetes mellitus. Orthologous to human PAX4 (paired box 4). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
ENSDARP00000013792 Paired box 1 123
ENSDARP00000013792 Homeodomain 163 219
ENSDARP00000140830 Paired box 15 139
ENSDARP00000140830 Homeodomain 179 236

Links

Other Homeodomain,Paired box family TFs
Other Danio rerio TFs

Invalid Input OrderBy

1 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action